<?xml version="1.0" encoding="ISO-8859-1"?><article xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance">
<front>
<journal-meta>
<journal-id>1646-5830</journal-id>
<journal-title><![CDATA[Acta Obstétrica e Ginecológica Portuguesa]]></journal-title>
<abbrev-journal-title><![CDATA[Acta Obstet Ginecol Port]]></abbrev-journal-title>
<issn>1646-5830</issn>
<publisher>
<publisher-name><![CDATA[Euromédice, Edições Médicas Lda.]]></publisher-name>
</publisher>
</journal-meta>
<article-meta>
<article-id>S1646-58302020000400257</article-id>
<title-group>
<article-title xml:lang="en"><![CDATA[Follicle-stimulating-hormone-secreting pituitary macroadenoma: a challenging diagnosis in gynecology]]></article-title>
<article-title xml:lang="pt"><![CDATA[Macroadenoma hipofisário secretor de hormona folículo-estimulante: um diagnóstico desafiante em ginecologia]]></article-title>
</title-group>
<contrib-group>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Peixinho]]></surname>
<given-names><![CDATA[Catarina]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Neves]]></surname>
<given-names><![CDATA[João Pedro]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Canão]]></surname>
<given-names><![CDATA[Pedro]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Bem]]></surname>
<given-names><![CDATA[Pedro]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Fortuna]]></surname>
<given-names><![CDATA[João]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
</contrib-group>
<aff id="Af1">
<institution><![CDATA[,Hospital Pedro Hispano Departamento de Ginecologia e Obstetrícia ]]></institution>
<addr-line><![CDATA[Matosinhos ]]></addr-line>
<country>Portugal</country>
</aff>
<aff id="Af2">
<institution><![CDATA[,Hospital Pedro Hispano Departamento de Ginecologia e Obstetrícia ]]></institution>
<addr-line><![CDATA[Matosinhos ]]></addr-line>
<country>Portugal</country>
</aff>
<aff id="Af3">
<institution><![CDATA[,Centro Hospitalar Universitário São João Departamento de Anatomia Patológica ]]></institution>
<addr-line><![CDATA[Porto ]]></addr-line>
<country>Portugal</country>
</aff>
<aff id="Af4">
<institution><![CDATA[,Hospital Pedro Hispano Departamento de Radiologia ]]></institution>
<addr-line><![CDATA[Matosinhos ]]></addr-line>
<country>Portugal</country>
</aff>
<aff id="Af5">
<institution><![CDATA[,Hospital Pedro Hispano Departamento de Ginecologia e Obstetricia ]]></institution>
<addr-line><![CDATA[Matosinhos ]]></addr-line>
<country>Portugal</country>
</aff>
<pub-date pub-type="pub">
<day>00</day>
<month>12</month>
<year>2020</year>
</pub-date>
<pub-date pub-type="epub">
<day>00</day>
<month>12</month>
<year>2020</year>
</pub-date>
<volume>14</volume>
<numero>4</numero>
<fpage>257</fpage>
<lpage>262</lpage>
<copyright-statement/>
<copyright-year/>
<self-uri xlink:href="http://scielo.pt/scielo.php?script=sci_arttext&amp;pid=S1646-58302020000400257&amp;lng=en&amp;nrm=iso"></self-uri><self-uri xlink:href="http://scielo.pt/scielo.php?script=sci_abstract&amp;pid=S1646-58302020000400257&amp;lng=en&amp;nrm=iso"></self-uri><self-uri xlink:href="http://scielo.pt/scielo.php?script=sci_pdf&amp;pid=S1646-58302020000400257&amp;lng=en&amp;nrm=iso"></self-uri><abstract abstract-type="short" xml:lang="en"><p><![CDATA[Abstract Menstrual irregularities account for up to 30% of outpatient visits to gynecologists. We present a case of a 29-year-old nulliparous woman with abnormal vaginal bleeding for the last five years. A transvaginal ultrasound revealed both ovaries enlarged with multiple cysts. Blood tests showed mildly elevated levels of estradiol and prolactin, and a suppressed LH. Cerebral MRI showed a pituitary macroadenoma. The patient was submitted to transsphenoidal surgery. The final diagnosis was pituitary adenoma with FSH and LH expression. Cases of pituitary adenomas causing clinical symptoms are unusual This diagnosis should be considered in women with menstrual irregularities and hyperstimulated ovaries.]]></p></abstract>
<kwd-group>
<kwd lng="en"><![CDATA[Follicle-stimulating-hormone]]></kwd>
<kwd lng="en"><![CDATA[Pituitary macroadenoma]]></kwd>
<kwd lng="en"><![CDATA[Menstrual irregularities]]></kwd>
<kwd lng="en"><![CDATA[Ovarian hyperstimulation]]></kwd>
<kwd lng="en"><![CDATA[Reproductive age.]]></kwd>
</kwd-group>
</article-meta>
</front><back>
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