<?xml version="1.0" encoding="ISO-8859-1"?><article xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance">
<front>
<journal-meta>
<journal-id>1646-5830</journal-id>
<journal-title><![CDATA[Acta Obstétrica e Ginecológica Portuguesa]]></journal-title>
<abbrev-journal-title><![CDATA[Acta Obstet Ginecol Port]]></abbrev-journal-title>
<issn>1646-5830</issn>
<publisher>
<publisher-name><![CDATA[Euromédice, Edições Médicas Lda.]]></publisher-name>
</publisher>
</journal-meta>
<article-meta>
<article-id>S1646-58302022000400327</article-id>
<title-group>
<article-title xml:lang="en"><![CDATA[Association between corpus luteum volume and the success of termination of pregnancy with mifepristone]]></article-title>
<article-title xml:lang="pt"><![CDATA[Associação entre o volume do corpo lúteo e o sucesso da interrupção da gravidez com mifepristona]]></article-title>
</title-group>
<contrib-group>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Rego]]></surname>
<given-names><![CDATA[Susana]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Reis-de-Carvalho]]></surname>
<given-names><![CDATA[Catarina]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Neves]]></surname>
<given-names><![CDATA[Joaquim]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Carvalho]]></surname>
<given-names><![CDATA[Rui]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
</contrib-group>
<aff id="Af1">
<institution><![CDATA[,Centro Hospitalar Universitário Lisboa Norte Hospital de Santa Maria Departamento de Obstetrícia, Ginecologia e Medicina da Reprodução]]></institution>
<addr-line><![CDATA[ ]]></addr-line>
<country>Portugal</country>
</aff>
<pub-date pub-type="pub">
<day>30</day>
<month>12</month>
<year>2022</year>
</pub-date>
<pub-date pub-type="epub">
<day>30</day>
<month>12</month>
<year>2022</year>
</pub-date>
<volume>16</volume>
<numero>4</numero>
<fpage>327</fpage>
<lpage>330</lpage>
<copyright-statement/>
<copyright-year/>
<self-uri xlink:href="http://scielo.pt/scielo.php?script=sci_arttext&amp;pid=S1646-58302022000400327&amp;lng=en&amp;nrm=iso"></self-uri><self-uri xlink:href="http://scielo.pt/scielo.php?script=sci_abstract&amp;pid=S1646-58302022000400327&amp;lng=en&amp;nrm=iso"></self-uri><self-uri xlink:href="http://scielo.pt/scielo.php?script=sci_pdf&amp;pid=S1646-58302022000400327&amp;lng=en&amp;nrm=iso"></self-uri><abstract abstract-type="short" xml:lang="en"><p><![CDATA[Abstract  Background:  Mifepristone is a progesterone antagonist often used in medical termination of pregnancy. One of its targets is the corpus luteum, the main source of progesterone in initial pregnancy maintenance. Corpus luteum volume is related to serum progesterone levels.  Objective:  This study intended to evaluate whether there is an association between corpus luteum volume and the success rate of pharmacological termination of pregnancy with mifepristone and misoprostol.  Methods:  This was a prospective, longitudinal, observational study. 176 women deciding to terminate their pregnancy were included. At the first medical visit we confirmed the presence of a viable pregnancy with less than 10 weeks and estimated corpus luteum volume by transvaginal ultrasound. Medical termination of pregnancy protocol in our hospital consisted of oral mifepristone 200 mg followed (24 hours) by oral misoprostol 200 µg one pill every hour until a maximum of eight doses. At the reevaluation visit, we registered clinical data and confirmed the success of the procedure by vaginal ultrasound.  Results:  The success rate of medical termination of pregnancy was 95.5%. No differences regarding corpus luteum volume were observed between successful and unsuccessful termination of pregnancy groups.  Conclusion:  In our sample there was no association between corpus luteum volume and the success rate of medical termination of pregnancy.]]></p></abstract>
<abstract abstract-type="short" xml:lang="pt"><p><![CDATA[Resumo  Introdução:  A mifepristona é um antagonista da progesterona frequentemente utilizado na interrupção médica da gravidez. Um dos seus alvos é o corpo lúteo, a principal fonte de progesterona na manutenção da gravidez inicial. O volume do corpo lúteo relaciona-se com os níveis séricos de progesterona.  Objetivo:  Este estudo teve como objetivo avaliar a existência de associação entre o volume do corpo lúteo e a taxa de sucesso da interrupção farmacológica da gravidez com mifepristona e misoprostol.  Métodos:  Este foi um estudo prospetivo, longitudinal e observacional. Foram incluídas 176 mulheres com intenção de interromper a gravidez. Na primeira consulta médica foi confirmada a presença de uma gravidez viável com menos de 10 semanas e estimado o volume do corpo lúteo por ecografia transvaginal. O protocolo de interrupção médica da gravidez no nosso hospital consistiu na administração de mifepristona oral 200 mg seguida (24 horas) de misoprostol oral 200 µg um comprimido a cada hora até ao máximo de oito doses. Na consulta de reavaliação foram registados dados clínicos e confirmado o sucesso do procedimento por ecografia vaginal.  Resultados:  A taxa de sucesso da interrupção médica da gravidez foi de 95,5%. Não foram observadas diferenças no volume do corpo lúteo entre os grupos de sucesso e insucesso da interrupção da gravidez.  Conclusão:  Nesta amostra no houve associação entre o volume do corpo lúteo e a taxa de sucesso da interrupção médica da gravidez.]]></p></abstract>
<kwd-group>
<kwd lng="en"><![CDATA[Corpus luteum]]></kwd>
<kwd lng="en"><![CDATA[Medical termination of pregnancy]]></kwd>
<kwd lng="en"><![CDATA[Mifepristone]]></kwd>
<kwd lng="en"><![CDATA[Progesterone]]></kwd>
<kwd lng="en"><![CDATA[Ultrasound]]></kwd>
<kwd lng="pt"><![CDATA[Corpo lúteo]]></kwd>
<kwd lng="pt"><![CDATA[Interrupção médica da gravidez]]></kwd>
<kwd lng="pt"><![CDATA[Mifepristona]]></kwd>
<kwd lng="pt"><![CDATA[Progesterona]]></kwd>
<kwd lng="pt"><![CDATA[Ecografia]]></kwd>
</kwd-group>
</article-meta>
</front><back>
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