<?xml version="1.0" encoding="ISO-8859-1"?><article xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance">
<front>
<journal-meta>
<journal-id>1646-706X</journal-id>
<journal-title><![CDATA[Angiologia e Cirurgia Vascular]]></journal-title>
<abbrev-journal-title><![CDATA[Angiol Cir Vasc]]></abbrev-journal-title>
<issn>1646-706X</issn>
<publisher>
<publisher-name><![CDATA[Sociedade Portuguesa de Angiologia e Cirurgia Vascular]]></publisher-name>
</publisher>
</journal-meta>
<article-meta>
<article-id>S1646-706X2011000200002</article-id>
<title-group>
<article-title xml:lang="pt"><![CDATA[Pé diabético]]></article-title>
<article-title xml:lang="en"><![CDATA[Diabetic foot]]></article-title>
</title-group>
<contrib-group>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Duarte]]></surname>
<given-names><![CDATA[Nádia]]></given-names>
</name>
</contrib>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Gonçalves]]></surname>
<given-names><![CDATA[Ana]]></given-names>
</name>
</contrib>
</contrib-group>
<aff id="A">
<institution><![CDATA[,  ]]></institution>
<addr-line><![CDATA[ ]]></addr-line>
</aff>
<pub-date pub-type="pub">
<day>00</day>
<month>06</month>
<year>2011</year>
</pub-date>
<pub-date pub-type="epub">
<day>00</day>
<month>06</month>
<year>2011</year>
</pub-date>
<volume>7</volume>
<numero>2</numero>
<fpage>65</fpage>
<lpage>79</lpage>
<copyright-statement/>
<copyright-year/>
<self-uri xlink:href="http://scielo.pt/scielo.php?script=sci_arttext&amp;pid=S1646-706X2011000200002&amp;lng=en&amp;nrm=iso"></self-uri><self-uri xlink:href="http://scielo.pt/scielo.php?script=sci_abstract&amp;pid=S1646-706X2011000200002&amp;lng=en&amp;nrm=iso"></self-uri><self-uri xlink:href="http://scielo.pt/scielo.php?script=sci_pdf&amp;pid=S1646-706X2011000200002&amp;lng=en&amp;nrm=iso"></self-uri><abstract abstract-type="short" xml:lang="pt"><p><![CDATA[Os problemas do pé são uma complicação comum da diabetes, com uma prevalência de 23-42% para a neuropatia, 9-23% - para a doença vascular e 5-7% - para a ulceração do pé. Estes, resultam em importantes consequências médicas, sociais e económicas para os doentes, respectiva família e sociedade. A ulceração do pé diabético está associada à doença vascular periférica e neuropatia periférica, frequentemente em combinação. No entanto, os indivíduos com um risco elevado de ulceração podem ser facilmente identificados através de um exame clínico cuidadoso dos seus pés, estando a educação e follow-up periódicos indicados nestes casos. Quando a úlcera do pé é complicada por uma infecção, a combinação pode ser ameaçadora para o membro e até para a vida. A infecção é definida clinicamente, mas as culturas ajudam na identificação dos agentes patogénicos responsáveis. A terapêutica antimicrobiana deve ser guiada pelos resultados das culturas e, embora esta terapêutica possa curar a infecção isoladamente, não cicatriza a úlcera, carecendo de correcção de outros factores (focos de pressão anómala, isquémia do membro) para lograr esta cicatrização.]]></p></abstract>
<abstract abstract-type="short" xml:lang="en"><p><![CDATA[Diabetic foot problems are a common complication of diabetes, with a prevalence of - 23-42% for neuropathy, 9-23% for vascular disease and 5-7% for foot ulceration. It, results in major medical, social and economic consequences for the patients, their families, and society. Diabetic foot ulceration is associated with peripheral vascular disease and peripheral neuropathy, often in combination. Individuals with the greatest risk of ulceration can easily be identified by careful clinical examination of their feet. Education and frequent follow-up is indicated for these patients. When a foot ulcer is complicated by an infection, the combination can be limb-threatening, or life-threatening. Infection is defined clinically, but wound cultures assist in identifying the causative pathogens. Antimicrobial therapy should be guided by culture results.., nevertheless such therapy, by itself, may cure the infection, but it does not heal the wound. To achieve that, it is also necessary to correct the other factors (abnormal pressure points, limb ischemia).]]></p></abstract>
<kwd-group>
<kwd lng="pt"><![CDATA[pé diabético]]></kwd>
<kwd lng="pt"><![CDATA[neuropatias diabéticas]]></kwd>
<kwd lng="pt"><![CDATA[doença arterial periférica]]></kwd>
<kwd lng="pt"><![CDATA[infecção e úlcera de pé]]></kwd>
<kwd lng="en"><![CDATA[diabetic foot]]></kwd>
<kwd lng="en"><![CDATA[diabetic neuropathies]]></kwd>
<kwd lng="en"><![CDATA[peripheral vascular diseases]]></kwd>
<kwd lng="en"><![CDATA[infection]]></kwd>
<kwd lng="en"><![CDATA[foot ulcer]]></kwd>
</kwd-group>
</article-meta>
</front><body><![CDATA[ <p><b>Pé diabético</b></p>     <p>&nbsp;</p>     <p><b>Nádia Duarte* e Ana Gonçalves**</b></p>     <p>* Interna do Internato Complementar de Angiologia e Cirurgia Vascular</p>     <p>** Assistente Graduada de Angiologia e Cirurgia Vascular</p>     <p><a name="top0"></a><a href="#0">Contactos</a></p>      <p>&nbsp;</p>     <p>|<b>RESUMO</b>|</p>     <p>Os problemas do pé são uma complicação comum da diabetes, com uma prevalência    de 23-42% para a neuropatia, 9-23% – para a doença vascular e 5-7% – para a    ulceração do pé. Estes, resultam em importantes consequências médicas, sociais    e económicas para os doentes, respectiva família e sociedade. A ulceração do    pé diabético está associada à doença vascular periférica e neuropatia periférica,    frequentemente em combinação. No entanto, os indivíduos com um risco elevado    de ulceração podem ser facilmente identificados através de um exame clínico    cuidadoso dos seus pés, estando a educação e follow-up periódicos indicados    nestes casos. Quando a úlcera do pé é complicada por uma infecção, a combinação    pode ser ameaçadora para o membro e até para a vida. A infecção é definida clinicamente,    mas as culturas ajudam na identificação dos agentes patogénicos responsáveis.    A terapêutica antimicrobiana deve ser guiada pelos resultados das culturas e,    embora esta terapêutica possa curar a infecção isoladamente, não cicatriza a    úlcera, carecendo de correcção de outros factores (focos de pressão anómala,    isquémia do membro) para lograr esta cicatrização. </p>     <p><b>Palavras-chave:</b> pé diabético, neuropatias diabéticas, doença arterial    periférica, infecção e úlcera de pé</p>     ]]></body>
<body><![CDATA[<p>&nbsp;</p>     <p><b>Diabetic foot</b></p>     <p>|<b>ABSTRACT</b>|</p>     <p>Diabetic foot problems are a common complication of diabetes, with a prevalence    of - 23-42% for neuropathy, 9-23% for vascular disease and 5-7% for foot ulceration.    It, results in major medical, social and economic consequences for the patients,    their families, and society. Diabetic foot ulceration is associated with peripheral    vascular disease and peripheral neuropathy, often in combination. Individuals    with the greatest risk of ulceration can easily be identified by careful clinical    examination of their feet. Education and frequent follow-up is indicated for    these patients. When a foot ulcer is complicated by an infection, the combination    can be limb-threatening, or life-threatening. Infection is defined clinically,    but wound cultures assist in identifying the causative pathogens. Antimicrobial    therapy should be guided by culture results.., nevertheless such therapy, by    itself, may cure the infection, but it does not heal the wound. To achieve that,    it is also necessary to correct the other factors (abnormal pressure points,    limb ischemia).</p>     <p><b>Key words</b><b>:</b> diabetic foot, diabetic neuropathies, peripheral vascular    diseases, infection, foot ulcer</p>     <p>&nbsp;</p>     <p>Texto completo disponível apenas em PDF.</p>     <p>Full text only available in PDF format.</p>     <p>&nbsp;</p>      <p><b>REFERÊNCIAS BIBLIOGRÁFICAS</b></p>     ]]></body>
<body><![CDATA[<p><sup>[1]</sup> Luís M. Alvim Serra . O Pé Diabético e a Prevenção da Catástrofe    (2001)</p>     <!-- ref --><p><sup>[2]</sup> Wild S et al. (2004) Global prevalence of diabetes:estimates    for 2000 and projections for 2030. DiabetesCare 27: 1047–1053&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;[&#160;<a href="javascript:void(0);" onclick="javascript: window.open('/scielo.php?script=sci_nlinks&ref=000024&pid=S1646-706X201100020000200001&lng=','','width=640,height=500,resizable=yes,scrollbars=1,menubar=yes,');">Links</a>&#160;]<!-- end-ref --><p><sup>[3]</sup> Harris M Rathur* and Andrew JM Boulton. The neuropathic diabetic    foot. Nature Clinical Practice Endocrinology &amp; Meetabolism pg 14 a 25</p>     <p><sup>[4]</sup> Benjamin A. Lipsky, Anthony R. Breendt, H. Gunner Deery, John    M.Embil, Warren S. Joseph, Adolf W. Karchmer, Jack L. LeFrock, Daniel P. Lew,    Jon T.Mader, Carl Norden, and James S. Tan. Diagnosis and Treatment of Diabetic    Foot Infections. Guidelines for Diabetic Foot Infections pg 885 a 910</p>     <p><sup>[5]</sup> Tomic-Canic M, Brem H. Gene array technology and pathogenesis    of chronic wounds. Am J Surg. Jul 2004;188(1A Suppl):67-72. <a href="http://www.medscape.com/medline/abstract/15223505" target="_blank">[Medline]</a>.</p>     <p><sup>[6]</sup> Directivas Práticas Sobre o Tratamento e a Prevenção do pé Diabético.International    Working Group on the Diabetic Foot. Sociedade Portuguesa de Diabetologia </p>     <p><sup>[7]</sup> Costa Almeida, A. Pratas Balhau, C. Pereira Alves, José Neves,    Mateus Mendes, L. Filipe Pinheiro, Aida Paulino. Pé Diabético, Recomendações    para o diagnóstico, profilaxia e tratamento. Sociedade Portuguesa de Cirurgia,    2006.</p>     <p><sup>[8]</sup> Mayfield JA, Sugarman JR. The use of the Semmes-Weinstein monofilament    and other threshold tests for preventing foot ulceration and amputation in persons    with diabetes. J Fam Pract. Nov 2000;49(11 Suppl):S17-29. <a href="http://www.medscape.com/medline/abstract/11093555" target="_blank">[Medline]</a>.</p>     <p><sup>[9]</sup> Singh N et al. (2005) Preventing foot ulcers in patients with    diabetes. JAMA 293: 217–228</p>     <p><sup>[10]</sup> King Sun Leong &amp;Philip Weston. Diabetes Ilustrada. Um guia    ilustrado sobre a diabetes e suas complicações</p>     ]]></body>
<body><![CDATA[<p><sup>[11]</sup> Reiber GE, Lipsky BA, Gibbons GW. The burden of diabetic foot    ulcers. Am J Surg. Aug 1998;176 (2A Suppl):5S-10S. <a href="http://www.medscape.com/medline/abstract/9777967" target="_blank">[Medline]</a>.</p>     <p><sup>[12]</sup> International Diabetes Federation (2005) Diabetes and Foot    Care: Time to Act. Brussels: International Diabetes Federation</p>     <p><sup>[13]</sup> Directivas Práticas Sobre o Tratamento e a Prevenção do pé    Diabético.International Working Group on the Diabetic Foot. Sociedade Portuguesa    de Diabetologia </p>     <p><sup>[14]</sup> Ramsey SD, Newton K, Blough D, McCulloch DK, Sandhu N, Reiber    GE, et al. Incidence, outcomes, and cost of foot ulcers in patients with diabetes.    Diabetes Care. Mar 1999;22(3):382-7. <a href="http://www.medscape.com/medline/abstract/10097914" target="_blank">[Medline]</a>.</p>     <p><sup>[15]</sup> Boyko EJ et al. (1996) Increased mortality associated with    diabetic foot ulcer. Diabet Med 13: 967–972</p>     <p><sup>[16]</sup> Harris M Rathur* and Andrew JM Boulton. The neuropathic diabetic    foot. Nature Clinical Practice Endocrinology &amp; Meetabolism pg 14 a 25</p>     <p>&nbsp;</p>     <p><b><a href="#top0">Contactos</a><a name="0"></a></b></p>     <p>Hospital Garcia de Orta</p>     <p>Av. Torrado da Silva,</p>     ]]></body>
<body><![CDATA[<p>Pragal, 2801-951 Almada;</p>     <p>telefone: 212727194</p>     <p><a href="mailto:duarte.nadia@gmail.com">duarte.nadia@gmail.com</a></p>     <p>(contacto para correspondência com a revista/correspondência com os leitores)    <a href="mailto:anag0706@gmail.com">anag0706@gmail.com</a></p>      ]]></body><back>
<ref-list>
<ref id="B1">
<label>2</label><nlm-citation citation-type="journal">
<person-group person-group-type="author">
<name>
<surname><![CDATA[Wild]]></surname>
<given-names><![CDATA[S]]></given-names>
</name>
</person-group>
<article-title xml:lang="en"><![CDATA[Global prevalence of diabetes: estimates for 2000 and projections for 2030]]></article-title>
<source><![CDATA[DiabetesCare]]></source>
<year>2004</year>
<volume>27</volume>
<page-range>1047-1053</page-range></nlm-citation>
</ref>
</ref-list>
</back>
</article>
