<?xml version="1.0" encoding="ISO-8859-1"?><article xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance">
<front>
<journal-meta>
<journal-id>2182-2395</journal-id>
<journal-title><![CDATA[Revista da Sociedade Portuguesa de Dermatologia e Venereologia]]></journal-title>
<abbrev-journal-title><![CDATA[Rev Soc Port Dermatol Venereol]]></abbrev-journal-title>
<issn>2182-2395</issn>
<publisher>
<publisher-name><![CDATA[Sociedade Portuguesa de Dermatologia e Venereologia]]></publisher-name>
</publisher>
</journal-meta>
<article-meta>
<article-id>S2182-23952021000300056</article-id>
<article-id pub-id-type="doi">10.29021/spdv.79.3.1340</article-id>
<title-group>
<article-title xml:lang="en"><![CDATA[Carcinoma Cuniculatum with Bone Invasion Mimicking a Viral Wart]]></article-title>
<article-title xml:lang="pt"><![CDATA[Carcinoma Cuniculatum com Invasão Óssea Mimetizando Verruga Viral]]></article-title>
</title-group>
<contrib-group>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Guerra]]></surname>
<given-names><![CDATA[Isabela Alves]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Simões]]></surname>
<given-names><![CDATA[Hisabella Lorena Porto]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Vieira]]></surname>
<given-names><![CDATA[Marcella Amaral Horta Barbosa]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Castañon]]></surname>
<given-names><![CDATA[Maria Christina Marques Nogueira]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
</contrib-group>
<aff id="Af1">
<institution><![CDATA[,Federal University of Juiz de Fora Teaching Hospital  ]]></institution>
<addr-line><![CDATA[Juiz de Fora ]]></addr-line>
<country>Brazil</country>
</aff>
<aff id="Af2">
<institution><![CDATA[,Lana&#8217;s Clinic  ]]></institution>
<addr-line><![CDATA[Juiz de Fora ]]></addr-line>
<country>Brazil</country>
</aff>
<aff id="Af3">
<institution><![CDATA[,Federal University of Juiz de Fora Institute of Biological Sciences ]]></institution>
<addr-line><![CDATA[Juiz de Fora ]]></addr-line>
<country>Brazil</country>
</aff>
<pub-date pub-type="pub">
<day>30</day>
<month>09</month>
<year>2021</year>
</pub-date>
<pub-date pub-type="epub">
<day>30</day>
<month>09</month>
<year>2021</year>
</pub-date>
<volume>79</volume>
<numero>3</numero>
<fpage>56</fpage>
<lpage>59</lpage>
<copyright-statement/>
<copyright-year/>
<self-uri xlink:href="http://scielo.pt/scielo.php?script=sci_arttext&amp;pid=S2182-23952021000300056&amp;lng=en&amp;nrm=iso"></self-uri><self-uri xlink:href="http://scielo.pt/scielo.php?script=sci_abstract&amp;pid=S2182-23952021000300056&amp;lng=en&amp;nrm=iso"></self-uri><self-uri xlink:href="http://scielo.pt/scielo.php?script=sci_pdf&amp;pid=S2182-23952021000300056&amp;lng=en&amp;nrm=iso"></self-uri><abstract abstract-type="short" xml:lang="en"><p><![CDATA[ABSTRACT Carcinoma cuniculatum is a rare variant of low-grade and well-differentiated squamous cell carcinoma. It is a locally invasive tumor, although it has low metastatic potential. It was originally described in the plantar region but may exceptionally appear in other locations. It predominates in middle-aged men and presents clinically as an exophytic, solitary, painful tumor, with insidious growth. Histologically, this tumor simulates a variety of benign dermatoses and may require several biopsies for the correct diagnosis. It is often misdiagnosed as a viral wart, due to the clinical similarity and the indolent course. The treatment of choice is surgical excision due to the high risk of recurrence and locally aggressive behavior. Amputation can be performed in cases of deep tissue invasion. We present a case of carcinoma cuniculatum in which the late diagnosis favored the invasion of the underlying bone, resulting in amputation of the affected finger.]]></p></abstract>
<abstract abstract-type="short" xml:lang="pt"><p><![CDATA[RESUMO Carcinoma cuniculatum é uma variante rara de carcinoma epidermoide de baixo grau e bem diferenciado. Trata-se de tumor local-mente invasivo, embora possua baixo potencial metastático. Originalmente descrito na região plantar pode excepcionalmente surgir noutras localizações. Predomina em homens de meia-idade e se apresenta clinicamente como tumor exofítico, solitário, doloroso, com crescimento insidioso. Histologicamente, este tumor simula uma variedade de dermatoses benignas, podendo exigir várias biópsias para o correto diagnóstico. Com frequência, é diagnosticado erroneamente como verruga viral, devido à semelhança clínica e ao curso indolente. O tratamento de escolha é a excisão cirúrgica pelo alto risco de recorrência e comportamento localmente agressivo. A amputação pode ser realizada em casos de invasão de tecidos profundos. Apresentamos um caso de carcinoma cuniculatum em que o diagnóstico tardio favoreceu a invasão do osso subjacente, resultando na amputação do quirodáctilo acometido.]]></p></abstract>
<kwd-group>
<kwd lng="en"><![CDATA[Carcinoma, Squamous Cell]]></kwd>
<kwd lng="en"><![CDATA[Carcinoma, Verrucous]]></kwd>
<kwd lng="en"><![CDATA[Neoplasm Invasiveness]]></kwd>
<kwd lng="en"><![CDATA[Warts.]]></kwd>
<kwd lng="pt"><![CDATA[Carcinoma de Células Escamosas]]></kwd>
<kwd lng="pt"><![CDATA[Invasividade Neoplásica]]></kwd>
<kwd lng="pt"><![CDATA[Verrugas.]]></kwd>
</kwd-group>
</article-meta>
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