<?xml version="1.0" encoding="ISO-8859-1"?><article xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance">
<front>
<journal-meta>
<journal-id>2183-5985</journal-id>
<journal-title><![CDATA[Acta Portuguesa de Nutrição]]></journal-title>
<abbrev-journal-title><![CDATA[Acta Port Nutr]]></abbrev-journal-title>
<issn>2183-5985</issn>
<publisher>
<publisher-name><![CDATA[Associação Portuguesa de Nutrição]]></publisher-name>
</publisher>
</journal-meta>
<article-meta>
<article-id>S2183-59852021000100076</article-id>
<article-id pub-id-type="doi">10.21011/apn.2021.2414</article-id>
<title-group>
<article-title xml:lang="pt"><![CDATA[SUCRALOSE: AMIGA OU INIMIGA?]]></article-title>
<article-title xml:lang="en"><![CDATA[SUCRALOSE: FRIEND OR ENEMY?]]></article-title>
</title-group>
<contrib-group>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Correia]]></surname>
<given-names><![CDATA[Daniela]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Delgado]]></surname>
<given-names><![CDATA[Mayumi Thaís]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Dinis]]></surname>
<given-names><![CDATA[Sofia Costa]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
</contrib-group>
<aff id="Af1">
<institution><![CDATA[,SonaeMC Granted Projects ]]></institution>
<addr-line><![CDATA[Matosinhos ]]></addr-line>
<country>Portugal</country>
</aff>
<aff id="Af2">
<institution><![CDATA[,Sonae MC Direção da Qualidade e Investigação ]]></institution>
<addr-line><![CDATA[Carnaxide ]]></addr-line>
<country>Portugal</country>
</aff>
<pub-date pub-type="pub">
<day>30</day>
<month>03</month>
<year>2021</year>
</pub-date>
<pub-date pub-type="epub">
<day>30</day>
<month>03</month>
<year>2021</year>
</pub-date>
<numero>24</numero>
<fpage>76</fpage>
<lpage>80</lpage>
<copyright-statement/>
<copyright-year/>
<self-uri xlink:href="http://scielo.pt/scielo.php?script=sci_arttext&amp;pid=S2183-59852021000100076&amp;lng=en&amp;nrm=iso"></self-uri><self-uri xlink:href="http://scielo.pt/scielo.php?script=sci_abstract&amp;pid=S2183-59852021000100076&amp;lng=en&amp;nrm=iso"></self-uri><self-uri xlink:href="http://scielo.pt/scielo.php?script=sci_pdf&amp;pid=S2183-59852021000100076&amp;lng=en&amp;nrm=iso"></self-uri><abstract abstract-type="short" xml:lang="pt"><p><![CDATA[RESUMO O uso de edulcorantes é uma estratégia para a diminuição do consumo de açúcar. A sucralose é dos mais utilizados, sendo descrita como segura por diferentes entidades de referência, como a Autoridade Europeia para a Segurança Alimentar e a Food &amp; Drug Administration. Mas sendo as publicações por tais entidades anteriores a 2017, torna-se importante atualizar o conhecimento científico. Foi feita uma pesquisa na base de dados Pubmed com o termo &#8220;sucralose AND health&#8221;, para os últimos 5 anos. Os principais temas abordados são a relação entre a ingestão de sucralose e a gestão da glicémia, ganho de peso, risco de desenvolvimento de síndrome metabólica e alteração da microbiota intestinal, com resultados, em geral, inconclusivos. Surgem estudos que levantam preocupações sobre exposição no útero e possível insegurança da sucralose, ainda pouco representativos. Contudo, perante a evidência atual, não é possível aferir que a sucralose leve a efeitos negativos na saúde, quando respeitado a ingestão diária aceitável (ADI, Acceptable Daily Intake).]]></p></abstract>
<abstract abstract-type="short" xml:lang="en"><p><![CDATA[ABSTRACT The use of sweeteners is a strategy for reducing sugar consumption. Sucralose is one of the most used, being described as safe by different reference entities, such as European Food Safety Authority and Food &amp; Drug Administration. But since the publications by these entities are prior to 2017, it is important to update scientific knowledge. A search was made in the Pubmed database with the term &#8220;sucralose AND health&#8221;, for the last 5 years. The main topics addressed are routes associated with blood glucose management, weight gain, metabolic syndrome and intestinal microbiota, with results in general inconclusive. Studies are emerging that raise concerns about exposure in the uterus and possible insecurity of sucralose. Even so, based on current evidence, it´s not possible to assess that sucralose leads to negative health effects, when the ADI is respected. But its use/consumption should be moderate, since the long-term effects are not fully known.]]></p></abstract>
<kwd-group>
<kwd lng="pt"><![CDATA[Edulcorantes]]></kwd>
<kwd lng="pt"><![CDATA[Saúde]]></kwd>
<kwd lng="pt"><![CDATA[Segurança Alimentar]]></kwd>
<kwd lng="pt"><![CDATA[Sucralose]]></kwd>
<kwd lng="en"><![CDATA[Sweeteners]]></kwd>
<kwd lng="en"><![CDATA[Health]]></kwd>
<kwd lng="en"><![CDATA[Food Safety]]></kwd>
<kwd lng="en"><![CDATA[Sucralose]]></kwd>
</kwd-group>
</article-meta>
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<given-names><![CDATA[A]]></given-names>
</name>
</person-group>
<article-title xml:lang=""><![CDATA[Low-/No-Calorie Sweeteners: A Review of Global Intakes.]]></article-title>
<source><![CDATA[Nutrients]]></source>
<year>2018</year>
<volume>10</volume>
<numero>3</numero>
<issue>3</issue>
<page-range>357</page-range></nlm-citation>
</ref>
</ref-list>
</back>
</article>
