<?xml version="1.0" encoding="ISO-8859-1"?><article xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance">
<front>
<journal-meta>
<journal-id>2183-5985</journal-id>
<journal-title><![CDATA[Acta Portuguesa de Nutrição]]></journal-title>
<abbrev-journal-title><![CDATA[Acta Port Nutr]]></abbrev-journal-title>
<issn>2183-5985</issn>
<publisher>
<publisher-name><![CDATA[Associação Portuguesa de Nutrição]]></publisher-name>
</publisher>
</journal-meta>
<article-meta>
<article-id>S2183-59852025000100036</article-id>
<article-id pub-id-type="doi">10.21011/apn.2025.4007</article-id>
<title-group>
<article-title xml:lang="pt"><![CDATA[O EFEITO DA SUPLEMENTAÇÃO DE ARGININA NA CICATRIZAÇÃO DE ÚLCERAS POR PRESSÃO: PROTOCOLO DE ESTUDO]]></article-title>
<article-title xml:lang="en"><![CDATA[THE EFFECT OF ARGININE SUPPLEMENTATION ON PRESSURE ULCER HEALING: STUDY PROTOCOL]]></article-title>
</title-group>
<contrib-group>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Vidinha]]></surname>
<given-names><![CDATA[Duarte]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Popa]]></surname>
<given-names><![CDATA[Cezara]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Moura]]></surname>
<given-names><![CDATA[Daiane]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Nunes]]></surname>
<given-names><![CDATA[Cláudia]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
</contrib-group>
<aff id="Af1">
<institution><![CDATA[,Agrupamento de Centros de Saúde Algarve Central I - Unidade Local de Saúde do Algarve Núcleo de Nutrição ]]></institution>
<addr-line><![CDATA[Faro ]]></addr-line>
<country>Portugal</country>
</aff>
<pub-date pub-type="pub">
<day>00</day>
<month>03</month>
<year>2025</year>
</pub-date>
<pub-date pub-type="epub">
<day>00</day>
<month>03</month>
<year>2025</year>
</pub-date>
<numero>40</numero>
<fpage>36</fpage>
<lpage>39</lpage>
<copyright-statement/>
<copyright-year/>
<self-uri xlink:href="http://scielo.pt/scielo.php?script=sci_arttext&amp;pid=S2183-59852025000100036&amp;lng=en&amp;nrm=iso"></self-uri><self-uri xlink:href="http://scielo.pt/scielo.php?script=sci_abstract&amp;pid=S2183-59852025000100036&amp;lng=en&amp;nrm=iso"></self-uri><self-uri xlink:href="http://scielo.pt/scielo.php?script=sci_pdf&amp;pid=S2183-59852025000100036&amp;lng=en&amp;nrm=iso"></self-uri><abstract abstract-type="short" xml:lang="pt"><p><![CDATA[RESUMO  INTRODUÇÃO:  É crescente o aumento da população idosa em Portugal e a procura de cuidados de saúde das Equipas de Cuidados Continuados Integrados no domicílio. Nestes utentes, as úlceras por pressão são uma das principais complicações relacionadas à imobilidade, aumento da morbilidade e diminuição da qualidade de vida. A evidência científica tem demonstrado o efeito positivo da alimentação e, em específico, da suplementação em arginina no processo de cicatrização de úlceras por pressão.  OBJETIVOS:  Avaliar os efeitos da suplementação em arginina na cicatrização de úlceras por pressão.  METODOLOGIA:  Este ensaio clínico não controlado irá incluir utentes com idade igual ou superior a 65 anos, acompanhados pela Equipas de Cuidados Continuados Integrados da Unidade de Cuidados na Comunidade de Faro que apresentem úlceras por pressão em estadios II, III ou IV. Os utentes serão divididos em três grupos: a) acompanhamento de enfermagem e acompanhamento alimentar/ nutricional, sem suplementação; b) acompanhamento de enfermagem e acompanhamento alimentar/nutricional, com suplementação de 5g/dia de arginina; c) acompanhamento de enfermagem e acompanhamento alimentar/nutricional, com suplementação de 10g/ dia de arginina. Todos os utentes serão acompanhados e avaliados durante 8 semanas. Serão recolhidos dados sociodemográficos, antropométricos, clínicos e de consumo alimentar. A cicatrização das úlceras por pressão será realizada através da aplicação da escala Pressure Ulcer Scale of Healing (PUSH).  RESULTADOS ESPERADOS:  Espera-se que este estudo, pioneiro na região e no país, na área dos cuidados domiciliários, possa vir a reforçar a evidência científica e contribuir para a melhoria da intervenção nutricional acerca da dose-resposta da arginina na cicatrização das úlceras por pressão. Face ao exposto, visa-se a melhoria da qualidade de vida dos utentes, do seu estado nutricional e, em última instância, a redução dos gastos em saúde.]]></p></abstract>
<abstract abstract-type="short" xml:lang="en"><p><![CDATA[ABSTRACT  INTRODUCTION:  There is a growing increase in the elderly population in Portugal and the demand for healthcare from Integrated Continuous Care Teams at home. In these patients, pressure ulcers are one of the main complications related to immobility, increased morbidity and decreased quality of life. Literature has demonstrated the positive effect of nutrition and, specifically, of arginine supplementation on the pressure ulcers healing process.  OBJECTIVES:  To evaluate the effects of arginine supplementation on pressure ulcers healing.  METHODOLOGY:  This uncontrolled clinical trial will include users aged 65 years or over, monitored by the Integrated Continuous Care Teams of the Care Unit in the Community of Faro who have pressure ulcers in stages II, III or IV. Users will be divided into three groups: (SS) nursing monitoring and food/nutritional monitoring, without supplementation; (S5) nursing monitoring and food/ nutritional monitoring, with supplementation of 5g/day of arginine; (S10) nursing monitoring and food/nutritional monitoring, with supplementation of 10g/day of arginine. All users will be monitored and evaluated for 8 weeks. Sociodemographic, anthropometric, clinical and food consumption data will be collected. Pressure ulcers healing will be carried out through the application of the Pressure Ulcer Scale of Healing.  EXPECTED RESULTS:  It is expected that this study, a pioneer project in the regional and national area, in home care, will reinforce scientific evidence and contribute to the improvement of nutritional intervention regarding the dose-response of arginine in the healing of pressure ulcers. In view of the above, the aim is to improve the quality of life of users, their nutritional status and, ultimately, the reduction of healthcare costs.]]></p></abstract>
<kwd-group>
<kwd lng="pt"><![CDATA[Arginina]]></kwd>
<kwd lng="pt"><![CDATA[Cicatrização]]></kwd>
<kwd lng="pt"><![CDATA[Suplementação Alimentar]]></kwd>
<kwd lng="pt"><![CDATA[Úlceras por Pressão]]></kwd>
<kwd lng="en"><![CDATA[Arginine]]></kwd>
<kwd lng="en"><![CDATA[Healing]]></kwd>
<kwd lng="en"><![CDATA[Dietary Supplementation]]></kwd>
<kwd lng="en"><![CDATA[Pressure Ulcers]]></kwd>
</kwd-group>
</article-meta>
</front><back>
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