<?xml version="1.0" encoding="ISO-8859-1"?><article xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance">
<front>
<journal-meta>
<journal-id>2184-0628</journal-id>
<journal-title><![CDATA[Gazeta Médica]]></journal-title>
<abbrev-journal-title><![CDATA[Gaz Med]]></abbrev-journal-title>
<issn>2184-0628</issn>
<publisher>
<publisher-name><![CDATA[Círculo Médico]]></publisher-name>
</publisher>
</journal-meta>
<article-meta>
<article-id>S2184-06282020000100038</article-id>
<article-id pub-id-type="doi">10.29315/gm.v7i1.304</article-id>
<title-group>
<article-title xml:lang="pt"><![CDATA[Um Caso Clínico de Sarcoidose Cutânea, Pulmonar, Esplénica e Neurosarcoidose]]></article-title>
<article-title xml:lang="en"><![CDATA[A Clinical Case of Cutaneous, Pulmonar, Splenic and Neurologic Sarcoidosis]]></article-title>
</title-group>
<contrib-group>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Machado]]></surname>
<given-names><![CDATA[Bela]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Matos]]></surname>
<given-names><![CDATA[Ana Rita]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Mendonça]]></surname>
<given-names><![CDATA[Teresa]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Farinha]]></surname>
<given-names><![CDATA[Fátima]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
</contrib-group>
<aff id="Af1">
<institution><![CDATA[,Hospital Central do Funchal  ]]></institution>
<addr-line><![CDATA[Funchal Madeira]]></addr-line>
<country>Portugal</country>
</aff>
<aff id="Af2">
<institution><![CDATA[,Hospital de Braga  ]]></institution>
<addr-line><![CDATA[Braga ]]></addr-line>
<country>Portugal</country>
</aff>
<aff id="Af3">
<institution><![CDATA[,Hospital Santo António Centro Hospitalar do Porto ]]></institution>
<addr-line><![CDATA[Porto ]]></addr-line>
<country>Portugal</country>
</aff>
<pub-date pub-type="pub">
<day>30</day>
<month>03</month>
<year>2020</year>
</pub-date>
<pub-date pub-type="epub">
<day>30</day>
<month>03</month>
<year>2020</year>
</pub-date>
<volume>7</volume>
<numero>1</numero>
<fpage>38</fpage>
<lpage>41</lpage>
<copyright-statement/>
<copyright-year/>
<self-uri xlink:href="http://scielo.pt/scielo.php?script=sci_arttext&amp;pid=S2184-06282020000100038&amp;lng=en&amp;nrm=iso"></self-uri><self-uri xlink:href="http://scielo.pt/scielo.php?script=sci_abstract&amp;pid=S2184-06282020000100038&amp;lng=en&amp;nrm=iso"></self-uri><self-uri xlink:href="http://scielo.pt/scielo.php?script=sci_pdf&amp;pid=S2184-06282020000100038&amp;lng=en&amp;nrm=iso"></self-uri><abstract abstract-type="short" xml:lang="pt"><p><![CDATA[Resumo A sarcoidose é uma doença granulomatosa que pode afetar qualquer órgão de etiologia desconhecida. Apresentamos o caso de um homem, de 49 anos, com antecedentes pessoais de um episódio de eritema nodoso. O estudo imagiológico do tórax mostrou múltiplas adenopatias mediastínicas e justa-hilares bilaterais, apesar de não apresentar queixas respiratórias. O lavado broncoalveolar revelou uma relação de células CD4/CD8 de 9,98 e o estudo analítico revelou uma enzima conversora da angiotensina elevada, sem outros achados. O doente iniciou corticoterapia verificando-se uma melhoria das manifestações cutâneas. Após dois anos, apresenta-se na consulta de Medicina Interna com queixas de emagrecimento, anorexia, fadiga, hipoacusia, síndrome vertiginosa e hipostesia dorsal em banda. Este caso mostra o envolvimento multissistémico da sarcoidose, tendo como ponto de partida para o seu diagnóstico uma manifestação cutânea e realça a importância da vigilância e do tratamento destes doentes a fim de um controlo atempado da doença.]]></p></abstract>
<abstract abstract-type="short" xml:lang="en"><p><![CDATA[Abstract Sarcoidosis is a granulomatous disorder that can affect any organ of unknown etiology. Presented is the study case of a male patient, 49-years of age with history of erythema nodosum. Upon performance of a thorax imagiological study it was visible multiple bilateral hilar and mediastinal adenopathy although there were no respiratory complaints. A bronchoalveolar lavage revealed a ratio of cells CD4/CD8 of 9.98 and the analytical study revealed a high angiotensin converting enzyme, without other findings. The patient started corticotherapy which improved his cutaneous manifestations. After two years, the patient presents to Internal medicine consultation complaining of weight loss, anorexia, fatigue, hypoacusic, episodic verdigo and spine hypoesthesia. This case shows the multisystemic involvement of sarcoidosis having as a starting point for its diagnosis a cutaneous manifestation and highlights the importance of monitoring and treating these patients for a timely and effective control of the disease.]]></p></abstract>
<kwd-group>
<kwd lng="pt"><![CDATA[Doenças da Pele]]></kwd>
<kwd lng="pt"><![CDATA[Doenças do Sistema Nervoso Central]]></kwd>
<kwd lng="pt"><![CDATA[Sarcoidose]]></kwd>
<kwd lng="pt"><![CDATA[Sarcoidose Pulmonar]]></kwd>
<kwd lng="en"><![CDATA[Central Nervous System Diseases]]></kwd>
<kwd lng="en"><![CDATA[Sarcoidosis]]></kwd>
<kwd lng="en"><![CDATA[Sarcoidosis, Pulmonary]]></kwd>
</kwd-group>
</article-meta>
</front><back>
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