<?xml version="1.0" encoding="ISO-8859-1"?><article xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance">
<front>
<journal-meta>
<journal-id>2184-0628</journal-id>
<journal-title><![CDATA[Gazeta Médica]]></journal-title>
<abbrev-journal-title><![CDATA[Gaz Med]]></abbrev-journal-title>
<issn>2184-0628</issn>
<publisher>
<publisher-name><![CDATA[Círculo Médico]]></publisher-name>
</publisher>
</journal-meta>
<article-meta>
<article-id>S2184-06282020000400356</article-id>
<article-id pub-id-type="doi">10.29315/gm.v7i4.327</article-id>
<title-group>
<article-title xml:lang="pt"><![CDATA[Síndrome de Marfan em Idade Pediátrica: Um Diagnóstico Raro nos Cuidados de Saúde Primários]]></article-title>
<article-title xml:lang="en"><![CDATA[Pediatric Marfan Syndrome: A Rare Diagnosis in Primary Health Care]]></article-title>
</title-group>
<contrib-group>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Costa]]></surname>
<given-names><![CDATA[Filipe]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Neto]]></surname>
<given-names><![CDATA[Cátia]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Silva]]></surname>
<given-names><![CDATA[Natércia]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Leite]]></surname>
<given-names><![CDATA[Ana Margarida]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Cunha]]></surname>
<given-names><![CDATA[Mário Antunes da]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
</contrib-group>
<aff id="Af1">
<institution><![CDATA[,USF S. Nicolau  ]]></institution>
<addr-line><![CDATA[Guimarães ]]></addr-line>
<country>Portugal</country>
</aff>
<aff id="Af2">
<institution><![CDATA[,USF Fafe Sentinela  ]]></institution>
<addr-line><![CDATA[Fafe ]]></addr-line>
<country>Portugal</country>
</aff>
<aff id="Af3">
<institution><![CDATA[,Centro Hospitalar do Tâmega e Sousa  ]]></institution>
<addr-line><![CDATA[Penafiel ]]></addr-line>
<country>Portugal</country>
</aff>
<aff id="Af4">
<institution><![CDATA[,USF S. Nicolau  ]]></institution>
<addr-line><![CDATA[Guimarães ]]></addr-line>
<country>Portugal</country>
</aff>
<pub-date pub-type="pub">
<day>30</day>
<month>12</month>
<year>2020</year>
</pub-date>
<pub-date pub-type="epub">
<day>30</day>
<month>12</month>
<year>2020</year>
</pub-date>
<volume>7</volume>
<numero>4</numero>
<fpage>356</fpage>
<lpage>360</lpage>
<copyright-statement/>
<copyright-year/>
<self-uri xlink:href="http://scielo.pt/scielo.php?script=sci_arttext&amp;pid=S2184-06282020000400356&amp;lng=en&amp;nrm=iso"></self-uri><self-uri xlink:href="http://scielo.pt/scielo.php?script=sci_abstract&amp;pid=S2184-06282020000400356&amp;lng=en&amp;nrm=iso"></self-uri><self-uri xlink:href="http://scielo.pt/scielo.php?script=sci_pdf&amp;pid=S2184-06282020000400356&amp;lng=en&amp;nrm=iso"></self-uri><abstract abstract-type="short" xml:lang="pt"><p><![CDATA[Resumo A síndrome de Marfan é uma das doenças hereditárias mais comuns do tecido conjuntivo, maioritariamente de transmissão autossómica dominante. Apresenta uma grande diversidade de manifestações clínicas, sendo clássico o envolvimento musculoesquelético, ocular e cardiovascular, embora seja também frequente o atingimento do pulmão, pele e sistema nervoso central. Descreve-se o caso de uma criança de 7 anos, do sexo masculino, que apresenta várias alterações ao exame objetivo que, juntamente com os achados dos exames complementares de diagnóstico, permitiram o diagnóstico desta síndrome. Trata-se de uma síndrome de Marfan, provavelmente esporádica, dada a ausência de história familiar, o que torna o caso ainda mais raro. O diagnóstico precoce da síndrome de Marfan é fulcral, permitindo diminuir o risco de complicações futuras, nomeadamente cardiovasculares, como a disseção ou rotura da aorta.]]></p></abstract>
<abstract abstract-type="short" xml:lang="en"><p><![CDATA[Abstract Marfan syndrome is one of the most common hereditary diseases of connective tissue, mostly of dominant autosomal transmission. There is a broad range of clinical manifestations, but the involvement of musculoskeletal, ocular and cardiovascular systems is classical, although the lung, skin and central nervous system are also frequently affected. This case is about a 7-year-old boy who presents several alterations in physical examination that, associated with the results of complementary diagnostic tests, led to the diagnosis of this syndrome. It is a Marfan syndrome, probably sporadic, given the absence of family history, which makes the case even rarer. An early diagnosis of Marfan syndrome is crucial to reduce the risk of future complications, including cardiovascular, such as dissection or rupture of the aorta.]]></p></abstract>
<kwd-group>
<kwd lng="pt"><![CDATA[Criança]]></kwd>
<kwd lng="pt"><![CDATA[Diagnóstico Diferencial]]></kwd>
<kwd lng="pt"><![CDATA[Síndrome de Marfan /diagnóstico]]></kwd>
<kwd lng="en"><![CDATA[Child]]></kwd>
<kwd lng="en"><![CDATA[Diagnosis, Differential]]></kwd>
<kwd lng="en"><![CDATA[Marfan Syndrome/diagnosis]]></kwd>
</kwd-group>
</article-meta>
</front><back>
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