<?xml version="1.0" encoding="ISO-8859-1"?><article xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance">
<front>
<journal-meta>
<journal-id>2184-0628</journal-id>
<journal-title><![CDATA[Gazeta Médica]]></journal-title>
<abbrev-journal-title><![CDATA[Gaz Med]]></abbrev-journal-title>
<issn>2184-0628</issn>
<publisher>
<publisher-name><![CDATA[Círculo Médico]]></publisher-name>
</publisher>
</journal-meta>
<article-meta>
<article-id>S2184-06282022000100067</article-id>
<article-id pub-id-type="doi">10.29315/gm.v1i1.446</article-id>
<title-group>
<article-title xml:lang="en"><![CDATA[An Unlikely Coronavirus Reinfection with Devastating Consequences: Interpreting Dynamic SARS-CoV-2 Test Result Through a Case Report]]></article-title>
<article-title xml:lang="pt"><![CDATA[Uma Improvável Reinfeção por Coronavírus com Consequências Devastadoras: Interpretando os Resultados Dinâmicos do Teste ao SARS-CoV-2 Através de um Caso Clínico]]></article-title>
</title-group>
<contrib-group>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Mendes]]></surname>
<given-names><![CDATA[João Lázaro]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Santos]]></surname>
<given-names><![CDATA[Cristina Mendes dos]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Salvador]]></surname>
<given-names><![CDATA[Mário Rui]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Lima]]></surname>
<given-names><![CDATA[Carla]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Cardoso]]></surname>
<given-names><![CDATA[Joana]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Almeida]]></surname>
<given-names><![CDATA[Isabela]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
</contrib-group>
<aff id="Af1">
<institution><![CDATA[,Centro Hospitalar Tondela-Viseu Serviço de Medicina Interna/ Internal Medicine Department ]]></institution>
<addr-line><![CDATA[Viseu ]]></addr-line>
<country>Portugal</country>
</aff>
<aff id="Af2">
<institution><![CDATA[,Agrupamento de Centros de Saúde do Dão-Lafões Unidade de Saúde Pública/ Public Health Unit ]]></institution>
<addr-line><![CDATA[Viseu ]]></addr-line>
<country>Portugal</country>
</aff>
<aff id="Af3">
<institution><![CDATA[,Centro Hospitalar Tondela-Viseu Serviço de Nefrologia/ Nefrology Department ]]></institution>
<addr-line><![CDATA[Viseu ]]></addr-line>
<country>Portugal</country>
</aff>
<pub-date pub-type="pub">
<day>30</day>
<month>03</month>
<year>2022</year>
</pub-date>
<pub-date pub-type="epub">
<day>30</day>
<month>03</month>
<year>2022</year>
</pub-date>
<volume>9</volume>
<numero>1</numero>
<fpage>67</fpage>
<lpage>70</lpage>
<copyright-statement/>
<copyright-year/>
<self-uri xlink:href="http://scielo.pt/scielo.php?script=sci_arttext&amp;pid=S2184-06282022000100067&amp;lng=en&amp;nrm=iso"></self-uri><self-uri xlink:href="http://scielo.pt/scielo.php?script=sci_abstract&amp;pid=S2184-06282022000100067&amp;lng=en&amp;nrm=iso"></self-uri><self-uri xlink:href="http://scielo.pt/scielo.php?script=sci_pdf&amp;pid=S2184-06282022000100067&amp;lng=en&amp;nrm=iso"></self-uri><abstract abstract-type="short" xml:lang="en"><p><![CDATA[Abstract A 40-year-old woman was admitted to hospital with fever and cough during the pandemic of COVID-19. Past medical was notable for advanced chronic kidney disease. On admission, nucleic acid testing of a nasopharyngeal swab was positive for SARS-CoV-2. After 11 days she was considered cure with two negative tests in a row. Eight weeks later, she was going to receive a kidney transplant from a deceased donor, but she was tested again for SARS-CoV-2 and the result came out positive. After that, surgery was cancelled. In our opinion, this test should not have been performed. Through this case we overview the knowledge about infectivity, reinfection and reactivation of SARS-CoV-2. We believe who has been considered cured in the last three months should undertake immunosuppression treatment in case of transplant or cancer treatment. In these cases, benefits outweigh the eventual risks for most patients.]]></p></abstract>
<abstract abstract-type="short" xml:lang="pt"><p><![CDATA[Resumo Uma utente com 40 anos de idade foi admitida no hospital por febre e tosse durante a pandemia da COVID-19. Na história médica passada destacava-se insuficiência renal crónica avançada. Na admissão, um teste de PCR de uma zaragatoa nasofaríngea foi positivo para SARS-CoV-2. Após 11 dias, a utente foi considerada curada, depois de 2 testes negativos. Passadas 8 semanas, foi convocada para transplante renal de um dador cadáver, mas foi novamente testada para SARS-CoV-2 e o resultado foi positivo. Depois disto, a cirurgia foi cancelada. Na nossa opinião, este teste não deveria ter sido realizado. A partir deste caso revemos o conhecimento atual sobre infetividade, reinfeção e reativação viral do SARS-CoV-2. Acreditamos que pacientes considerados curados nos últimos 3 meses devem fazer imunossupressão caso esta esteja indicada em contexto de neoplasia ou transplante. Nestes casos, os benefícios compensam o eventual risco para a maioria dos utentes.]]></p></abstract>
<kwd-group>
<kwd lng="en"><![CDATA[Coronavirus Infections/diagnosis]]></kwd>
<kwd lng="en"><![CDATA[COVID-19]]></kwd>
<kwd lng="en"><![CDATA[Infection Control]]></kwd>
<kwd lng="en"><![CDATA[Pandemics]]></kwd>
<kwd lng="pt"><![CDATA[Controlo de infeções]]></kwd>
<kwd lng="pt"><![CDATA[COVID-19]]></kwd>
<kwd lng="pt"><![CDATA[Infeção por Coronavírus]]></kwd>
<kwd lng="pt"><![CDATA[Pandemia]]></kwd>
</kwd-group>
</article-meta>
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