<?xml version="1.0" encoding="ISO-8859-1"?><article xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance">
<front>
<journal-meta>
<journal-id>2184-0628</journal-id>
<journal-title><![CDATA[Gazeta Médica]]></journal-title>
<abbrev-journal-title><![CDATA[Gaz Med]]></abbrev-journal-title>
<issn>2184-0628</issn>
<publisher>
<publisher-name><![CDATA[Círculo Médico]]></publisher-name>
</publisher>
</journal-meta>
<article-meta>
<article-id>S2184-06282024000100021</article-id>
<article-id pub-id-type="doi">10.29315/gm.v1i1.729</article-id>
<title-group>
<article-title xml:lang="pt"><![CDATA[Probióticos na Prevenção de Otite Média Aguda em Idade Pediátrica: Uma Revisão Baseada na Evidência]]></article-title>
<article-title xml:lang="en"><![CDATA[Probiotics in the Prevention of Acute Otitis Media in Pediatrics: An Evidence-Based Review]]></article-title>
</title-group>
<contrib-group>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Marques]]></surname>
<given-names><![CDATA[Ana Borges dos Santos]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Vieira]]></surname>
<given-names><![CDATA[Cecília Fernandes]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
</contrib-group>
<aff id="Af1">
<institution><![CDATA[,Agrupamento de Centros de Saúde de Gondomar Unidade de Saúde Familiar Despertar ]]></institution>
<addr-line><![CDATA[Gondomar ]]></addr-line>
<country>Portugal</country>
</aff>
<aff id="Af2">
<institution><![CDATA[,Unidade Local de Saúde de Matosinhos Unidade de Saúde Familiar Leça ]]></institution>
<addr-line><![CDATA[Matosinhos ]]></addr-line>
<country>Portugal</country>
</aff>
<pub-date pub-type="pub">
<day>30</day>
<month>03</month>
<year>2024</year>
</pub-date>
<pub-date pub-type="epub">
<day>30</day>
<month>03</month>
<year>2024</year>
</pub-date>
<volume>11</volume>
<numero>1</numero>
<fpage>21</fpage>
<lpage>27</lpage>
<copyright-statement/>
<copyright-year/>
<self-uri xlink:href="http://scielo.pt/scielo.php?script=sci_arttext&amp;pid=S2184-06282024000100021&amp;lng=en&amp;nrm=iso"></self-uri><self-uri xlink:href="http://scielo.pt/scielo.php?script=sci_abstract&amp;pid=S2184-06282024000100021&amp;lng=en&amp;nrm=iso"></self-uri><self-uri xlink:href="http://scielo.pt/scielo.php?script=sci_pdf&amp;pid=S2184-06282024000100021&amp;lng=en&amp;nrm=iso"></self-uri><abstract abstract-type="short" xml:lang="pt"><p><![CDATA[Resumo A otite média aguda (OMA) é uma patologia frequente em idade pediátrica, associando-se a elevada prescrição de antibióticos e importantes custos socioeconómicos. A utilização de probióticos revelou-se benéfica e segura noutras infeções. O presente trabalho pretendeu avaliar a associação entre os probióticos e a prevenção da ocorrência e diminuição do impacto da OMA em idade pediátrica. Para o efeito realizou-se uma pesquisa sobre o tema nas principais bases de dados de medicina baseada na evidência, tendo-se selecionado uma revisão sistemática com meta-análise e dois ensaios clínicos. Os artigos incluídos sugerem que os probióticos são eficazes na prevenção da OMA em idade pediátrica, com bom perfil de segurança. No entanto, os estudos são heterogéneos e mostraram resultados inconsistentes, classificando-se a força de recomendação como B pela escala SORT. As estirpes eficazes e a melhor posologia carecem de determinação em estudos de maior qualidade metodológica, dimensão e duração.]]></p></abstract>
<abstract abstract-type="short" xml:lang="en"><p><![CDATA[Abstract Acute otitis media (AOM) is a common disease in children and a leading cause of antibiotic prescription, representing a significant socioeconomic burden. Probiotics have revealed beneficial results in other infections with a good safety profile. This review aimed to assess the effects of probiotics in preventing the occurrence of AOM at pediatric age and reducing its impact. For this purpose, a literature search was conducted in evidence-based medicine databases. One meta-analysis and two clinical trials were included in this review. Evidence suggests that the administration of probiotics is effective in preventing AOM, with a good safety profile. However, the studies were heterogeneous and showed inconsistent results. Therefore, the strength of recommendation was classified as B using the SORT scale. Studies with larger sample sizes, longer durations, and better quality are needed to determine the optimal strain, duration, frequency, and timing of probiotic administration.]]></p></abstract>
<kwd-group>
<kwd lng="pt"><![CDATA[Criança]]></kwd>
<kwd lng="pt"><![CDATA[Otite Média aguda]]></kwd>
<kwd lng="pt"><![CDATA[Probióticos]]></kwd>
<kwd lng="en"><![CDATA[Child]]></kwd>
<kwd lng="en"><![CDATA[Otitis Media]]></kwd>
<kwd lng="en"><![CDATA[Probiotics]]></kwd>
</kwd-group>
</article-meta>
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