<?xml version="1.0" encoding="ISO-8859-1"?><article xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance">
<front>
<journal-meta>
<journal-id>2341-4545</journal-id>
<journal-title><![CDATA[GE-Portuguese Journal of Gastroenterology]]></journal-title>
<abbrev-journal-title><![CDATA[GE Port J Gastroenterol]]></abbrev-journal-title>
<issn>2341-4545</issn>
<publisher>
<publisher-name><![CDATA[Sociedade Portuguesa de Gastrenterologia]]></publisher-name>
</publisher>
</journal-meta>
<article-meta>
<article-id>S2341-45452021000500354</article-id>
<article-id pub-id-type="doi">10.1159/000510784</article-id>
<title-group>
<article-title xml:lang="en"><![CDATA[Infectious Proctitis in Ulcerative Colitis: The Importance of an Accurate Differential Diagnosis]]></article-title>
<article-title xml:lang="pt"><![CDATA[Proctite infeciosa em doente com colite ulcerosa: a importância do diagnóstico diferencial preciso]]></article-title>
</title-group>
<contrib-group>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Saraiva]]></surname>
<given-names><![CDATA[Miguel Mascarenhas]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Ribeiro]]></surname>
<given-names><![CDATA[Tiago Filipe]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Macedo]]></surname>
<given-names><![CDATA[Guilherme]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
<xref ref-type="aff" rid="Aaf"/>
</contrib>
</contrib-group>
<aff id="Af1">
<institution><![CDATA[,Centro Hospitalar Universitário de São João Gastroenterology Department ]]></institution>
<addr-line><![CDATA[Porto ]]></addr-line>
<country>Portugal</country>
</aff>
<aff id="Af2">
<institution><![CDATA[,University of Porto Faculty of Medicine ]]></institution>
<addr-line><![CDATA[Porto ]]></addr-line>
<country>Portugal</country>
</aff>
<pub-date pub-type="pub">
<day>30</day>
<month>10</month>
<year>2021</year>
</pub-date>
<pub-date pub-type="epub">
<day>30</day>
<month>10</month>
<year>2021</year>
</pub-date>
<volume>28</volume>
<numero>5</numero>
<fpage>354</fpage>
<lpage>359</lpage>
<copyright-statement/>
<copyright-year/>
<self-uri xlink:href="http://scielo.pt/scielo.php?script=sci_arttext&amp;pid=S2341-45452021000500354&amp;lng=en&amp;nrm=iso"></self-uri><self-uri xlink:href="http://scielo.pt/scielo.php?script=sci_abstract&amp;pid=S2341-45452021000500354&amp;lng=en&amp;nrm=iso"></self-uri><self-uri xlink:href="http://scielo.pt/scielo.php?script=sci_pdf&amp;pid=S2341-45452021000500354&amp;lng=en&amp;nrm=iso"></self-uri><abstract abstract-type="short" xml:lang="en"><p><![CDATA[Abstract: The authors present the case of a 62-year-old male presenting with a relapse of ulcerative colitis. He had unprotected anal intercourse with other men and his medical record was remarkable for HIV infection. He was admitted to the emergency department with bloody diarrhea, tenesmus, urgency, and recent weight loss. Laboratory workup revealed de novo mild anemia and mild elevation of inflammation parameters. Endoscopic evaluation displayed loss of normal vascular pattern, edema, erythema, exudation, and superficial ulceration in the distal rectum. Biopsies showed chronic proctitis with mild to moderate activity. The patient was treated with intravenous glucocorticoids, but symptoms persisted. Extensive microbial study allowed the identification of multiple infectious agents with potential for infectious proctitis: cytomegalovirus, Chlamydia trachomatis, and Blastocystis hominis. This case highlights the importance of careful microbial investigation, supporting a detailed clinical history, in patients presenting with symptoms of inflammatory bowel disease flare, particularly in risk groups such as that with sexual risk.]]></p></abstract>
<abstract abstract-type="short" xml:lang="pt"><p><![CDATA[Resumo: Os autores descrevem o caso de um indivíduo do sexo masculino, com infeção pelo vírus da imunodeficiência humana, admitido por agudização de colite ulcerosa. O doente descreve prática de sexo anal desprotegido. No serviço de urgência apresentava-se com queixas de diarreia sanguinolenta, tenesmo, falsas vontades e perda recente de peso. Do estudo efetuado, analiticamente apresentava-se com anemia ligeira de novo, e com elevação ligeira dos parâmetros inflamatórios. A retossigmoidoscopia flexível realizada apresentava disrupção do normal padrão vascular, edema, eritema, exsudação e ulceração superficial do reto distal. Foram realizadas biópsias das lesões que demonstraram sinais de proctite crónica com atividade ligeira a moderada. Atendendo à gravidade do quadro, o doente iniciou corticoterapia endovenosa, porém sem resolução dos sintomas. Uma avaliação microbiológica extensa permitiu a identificação de diversos agentes com potencial para causar proctite infeciosa: citomegalovírus, Chlamydia trachomatise Blastocystis hominis. Este caso realça a importância do estudo microbiológico, a suportar uma história clínica detalhada, em doentes que se apresentam com sintomatologia sugestiva de exacerbação de doença inflamatória intestinal.]]></p></abstract>
<kwd-group>
<kwd lng="en"><![CDATA[Blastocystis hominis]]></kwd>
<kwd lng="en"><![CDATA[Ulcerative colitis]]></kwd>
<kwd lng="en"><![CDATA[Cytomegalovirus]]></kwd>
<kwd lng="en"><![CDATA[Infectious proctitis]]></kwd>
<kwd lng="en"><![CDATA[Lymphogranuloma venereum]]></kwd>
<kwd lng="pt"><![CDATA[Blastocystis hominis]]></kwd>
<kwd lng="pt"><![CDATA[Colite ulcerosa]]></kwd>
<kwd lng="pt"><![CDATA[Citomegalovírus]]></kwd>
<kwd lng="pt"><![CDATA[Proctite infeciosa]]></kwd>
<kwd lng="pt"><![CDATA[Linfogranuloma venéreo]]></kwd>
</kwd-group>
</article-meta>
</front><back>
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