<?xml version="1.0" encoding="ISO-8859-1"?><article xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance">
<front>
<journal-meta>
<journal-id>2341-4545</journal-id>
<journal-title><![CDATA[GE-Portuguese Journal of Gastroenterology]]></journal-title>
<abbrev-journal-title><![CDATA[GE Port J Gastroenterol]]></abbrev-journal-title>
<issn>2341-4545</issn>
<publisher>
<publisher-name><![CDATA[Sociedade Portuguesa de Gastrenterologia]]></publisher-name>
</publisher>
</journal-meta>
<article-meta>
<article-id>S2341-45452021000600416</article-id>
<article-id pub-id-type="doi">10.1159/000511647</article-id>
<title-group>
<article-title xml:lang="en"><![CDATA[Rectal Perforation by a Balloon Spacer: A Rare Cause of Rectal Perforation Addressed Endoscopically]]></article-title>
<article-title xml:lang="pt"><![CDATA[Perfuração rectal por balloon spacer: uma causa rara de perfuração com resolução endoscópica]]></article-title>
</title-group>
<contrib-group>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Barros]]></surname>
<given-names><![CDATA[Sónia]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Roseira]]></surname>
<given-names><![CDATA[Joana]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Caldeira]]></surname>
<given-names><![CDATA[Paulo]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Vaz]]></surname>
<given-names><![CDATA[Ana Margarida]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Guerreiro]]></surname>
<given-names><![CDATA[Horácio]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Codon]]></surname>
<given-names><![CDATA[Oscar]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
</contrib-group>
<aff id="Af1">
<institution><![CDATA[,Algarve University Medical Center Gastroenterology Department ]]></institution>
<addr-line><![CDATA[Faro ]]></addr-line>
<country>Portugal</country>
</aff>
<aff id="Af2">
<institution><![CDATA[,Algarve Radio-Oncology Clinic Radiation Oncology Department ]]></institution>
<addr-line><![CDATA[Faro ]]></addr-line>
<country>Portugal</country>
</aff>
<pub-date pub-type="pub">
<day>30</day>
<month>12</month>
<year>2021</year>
</pub-date>
<pub-date pub-type="epub">
<day>30</day>
<month>12</month>
<year>2021</year>
</pub-date>
<volume>28</volume>
<numero>6</numero>
<fpage>416</fpage>
<lpage>419</lpage>
<copyright-statement/>
<copyright-year/>
<self-uri xlink:href="http://scielo.pt/scielo.php?script=sci_arttext&amp;pid=S2341-45452021000600416&amp;lng=en&amp;nrm=iso"></self-uri><self-uri xlink:href="http://scielo.pt/scielo.php?script=sci_abstract&amp;pid=S2341-45452021000600416&amp;lng=en&amp;nrm=iso"></self-uri><self-uri xlink:href="http://scielo.pt/scielo.php?script=sci_pdf&amp;pid=S2341-45452021000600416&amp;lng=en&amp;nrm=iso"></self-uri><abstract abstract-type="short" xml:lang="en"><p><![CDATA[Abstract: Prostate cancer is the second most frequent cancer in men worldwide. Dose escalation is currently the standard of care for the treatment of prostate cancer with radiation therapy. However, the rectum tends to be the dose-limiting structure when treating prostate cancer, given its proximity. The injection of biodegradable spacers between the prostate and the rectum may optimize radiotherapy treatment delivery for patients with localized disease. Nevertheless, although the overall complication rate of spacers is marginal, the benefits of spacer technologies need to be evaluated against the complication risks such as rectum perforation/necrosis. We report a case of a 59-year-old man with a diagnosis of prostate adenocarcinoma for whom hormonal treatment followed by intensity modulated radiation therapy (IMRT) was proposed. A biodegradable and expandable balloon (BioProtect®) was injected into the perirectal space without detectable immediate complications. One month later, the patient presented with a 3-day persistent rectal bleeding. The investigation confirmed a rectal perforation by the balloon spacer system.]]></p></abstract>
<abstract abstract-type="short" xml:lang="pt"><p><![CDATA[Resumo: O cancro da próstata é atualmente, em todo o mundo, o segundo cancro mais frequente no homem. As recomendações atuais indicam o uso doses de radiação progressivamente maiores ao longo do processo de radioterapia no tratamento do cancro da próstata. Contudo, a proximidade anatómica do reto é um fator limitante na dose de radiação usada ao longo do tratamento. A colocação de espaçadores biodegradáveis entre a próstata e o reto pode otimizar o tratamento de radioterapia em doentes com doença localizada. No entanto, embora a taxa de complicações dos espaçadores seja reduzida, o benefício desta técnica precisa de ser contrabalançada com o risco de complicações, como perfuração/necrose do reto. Apresentamos o caso de um paciente do sexo masculino de 59 anos com diagnóstico de adenocarcinoma da próstata para o qual foi proposto tratamento hormonal seguido de radioterapia com intensidade modulada (IMRT). Um balão biodegradável e expansível (BioProtect®) foi injetado no espaço peri-retal sem complicações imediatas detetáveis. Após um mês, o paciente apresentou hematoquézias persistentes durante três dias. A investigação confirmou tratar-se de uma perfuração retal pelo balloon spacer.]]></p></abstract>
<kwd-group>
<kwd lng="en"><![CDATA[Intensity-modulated radiotherapy]]></kwd>
<kwd lng="en"><![CDATA[Adverse effects]]></kwd>
<kwd lng="en"><![CDATA[Rectal spacer]]></kwd>
<kwd lng="en"><![CDATA[Rectal perforation]]></kwd>
<kwd lng="en"><![CDATA[Endoscopy]]></kwd>
<kwd lng="pt"><![CDATA[Radioterapia com intensidade modulada]]></kwd>
<kwd lng="pt"><![CDATA[Efeitos adversos]]></kwd>
<kwd lng="pt"><![CDATA[Rectal spacer]]></kwd>
<kwd lng="pt"><![CDATA[Perfuração retal]]></kwd>
<kwd lng="pt"><![CDATA[Endoscopia]]></kwd>
</kwd-group>
</article-meta>
</front><back>
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