<?xml version="1.0" encoding="ISO-8859-1"?><article xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance">
<front>
<journal-meta>
<journal-id>2341-4545</journal-id>
<journal-title><![CDATA[GE-Portuguese Journal of Gastroenterology]]></journal-title>
<abbrev-journal-title><![CDATA[GE Port J Gastroenterol]]></abbrev-journal-title>
<issn>2341-4545</issn>
<publisher>
<publisher-name><![CDATA[Sociedade Portuguesa de Gastrenterologia]]></publisher-name>
</publisher>
</journal-meta>
<article-meta>
<article-id>S2341-45452021000600420</article-id>
<article-id pub-id-type="doi">10.1159/000512088</article-id>
<title-group>
<article-title xml:lang="en"><![CDATA[Cannabinoid Hyperemesis Syndrome: A Case Report of an Underdiagnosed Condition]]></article-title>
<article-title xml:lang="pt"><![CDATA[Síndrome hiperemética dos Canabinóides: um caso clínico de uma patologia subdiagnosticada]]></article-title>
</title-group>
<contrib-group>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Nogueira]]></surname>
<given-names><![CDATA[João Machado]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Fonseca]]></surname>
<given-names><![CDATA[Inês]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Duarte]]></surname>
<given-names><![CDATA[Marco]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
</contrib-group>
<aff id="Af1">
<institution><![CDATA[,Centro Hospitalar de Setúbal Departamento de Psiquiatria e Saúde Mental ]]></institution>
<addr-line><![CDATA[Setúbal ]]></addr-line>
<country>Portugal</country>
</aff>
<pub-date pub-type="pub">
<day>30</day>
<month>12</month>
<year>2021</year>
</pub-date>
<pub-date pub-type="epub">
<day>30</day>
<month>12</month>
<year>2021</year>
</pub-date>
<volume>28</volume>
<numero>6</numero>
<fpage>420</fpage>
<lpage>424</lpage>
<copyright-statement/>
<copyright-year/>
<self-uri xlink:href="http://scielo.pt/scielo.php?script=sci_arttext&amp;pid=S2341-45452021000600420&amp;lng=en&amp;nrm=iso"></self-uri><self-uri xlink:href="http://scielo.pt/scielo.php?script=sci_abstract&amp;pid=S2341-45452021000600420&amp;lng=en&amp;nrm=iso"></self-uri><self-uri xlink:href="http://scielo.pt/scielo.php?script=sci_pdf&amp;pid=S2341-45452021000600420&amp;lng=en&amp;nrm=iso"></self-uri><abstract abstract-type="short" xml:lang="en"><p><![CDATA[Abstract: Cannabinoid hyperemesis syndrome (CHS) is characterized by episodic bursts of nausea, vomiting and abdominal pain, affecting chronic cannabis users. The clinical picture mimics an acute abdomen, usually leading to multiple assessments in the emergency department. Several complementary diagnostic examinations are performed with non-specific results, making differential diagnosis puzzling. We present a case of a 42-year-old man, who has been admitted multiple times to the emergency department in the last 3 months for abdominal pain, nausea and vomiting, without triggering factors and improving only with hot water baths. He was evaluated by different specialties, the various complementary diagnostic tests performed showed no significant results, and no definitive diagnosis was obtained. Treatment resulted only in a partial and transient resolution of symptoms. A more detailed medical history revealed cannabis use for more than 5 years, with a recent increase in the amount consumed. After psychoeducation, explaining the risks associated with consumption and its relationship with the clinical symptoms, which resulted in complete suspension of cannabis, there have been no new symptomatic episodes since then. We present an illustrative case of a poorly reported clinical entity despite having a probable significant prevalence, raising awareness in order that clinicians identify and properly manage these cases.]]></p></abstract>
<abstract abstract-type="short" xml:lang="pt"><p><![CDATA[Resumo: A Síndrome Hiperemética dos Canabinóides cursa com crises episódicas de náuseas, vómitos e dor abdominal que acometem consumidores crónicos de cannabis. O quadro clínico mimetiza o de um abdómen agudo, condicionando habitualmente múltiplas avaliações no Serviço de Urgência (SU) que levam à realização de vários exames complementares de diagnóstico (ECD), cujos resultados tendem a ser inespecíficos, dificultando o diagnóstico diferencial. Apresentamos o caso de um homem de 42 anos de idade, sem antecedentes psiquiátricos conhecidos, que nos últimos 3 meses foi admitido por múltiplas vezes no SU Hospitalar por dor abdominal, náuseas e vómitos aliviados com banhos de água quente. Vários exames auxiliares de diagnóstico e avaliação por diferentes especialidades foram realizados, sem que se obtivesse um diagnóstico definitivo. A terapêutica sintomática instituída resultou apenas numa resolução parcial e transitória dos sintomas. Uma história clínica mais detalhada revelou um consumo de cannabis há mais de 5 anos, com incremento recente da quantidade consumida. Após psicoeducação ao doente, explicando os riscos do consumo de canabinóides e a sua relação com a sintomatologia apresentada resultou na suspensão completa no consumo de cannabis, não se tendo verificado novos episódios sintomáticos desde então. Este é um caso ilustrativo de uma entidade clínica recente, cuja prevalência está a aumentar, tendo em conta o aumento do consumo de cannabis. A adequada identificação desta patologia é fundamental para um tratamento adequado e eficaz, evitando o uso desnecessário de métodos complementares de diagnóstico e medicação.]]></p></abstract>
<kwd-group>
<kwd lng="en"><![CDATA[Cannabis]]></kwd>
<kwd lng="en"><![CDATA[Cannabinoid]]></kwd>
<kwd lng="en"><![CDATA[Hyperemesis]]></kwd>
<kwd lng="en"><![CDATA[Cyclic vomiting]]></kwd>
<kwd lng="en"><![CDATA[Case report]]></kwd>
<kwd lng="pt"><![CDATA[Cannabis]]></kwd>
<kwd lng="pt"><![CDATA[Canabinóides]]></kwd>
<kwd lng="pt"><![CDATA[Hiperémese]]></kwd>
<kwd lng="pt"><![CDATA[Vómitos cíclicos]]></kwd>
<kwd lng="pt"><![CDATA[Caso-clínico]]></kwd>
</kwd-group>
</article-meta>
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