2341-4545 2341-4545 S2341-45452022000400074 10.1159/000515673 Portugal 30 08 2022 30 08 2022 29 4 74 76 1 2020 2 2014 2014 bcr2014203756 3 1986 29 8 8 511-4 4 1981 75 6 6 445-8 5 1989 49 2 2 189-91