2504-3145 2504-3145 S2504-31452020000300176 10.1159/000512564 Portugal Portugal Portugal 00 08 2020 00 08 2020 38 3 176 186

1 2020 23 6 6 812-23 2 2002 137 6 6 511-20 3 2013 369 19 19 1777-9 4 2013 91 10 10 50-70 5 2010 363 26 26 2477-81 6 2006 7 2011 89 9 9 46-52 8 2016 19 6 6 903-8 9 1988 25 1 1 37-50 10 2017 13 3 3 189-92 11 2019 26 3 3 798-815 12 2002 2 4 4 319-26 13 2017 356 j437 14 1975 5 15 1999 6 16 2019 12 17 2020 13 18 2018 11 1 1 1447828 19 1988 26 3 3 369-88 20 1913 21 2009 12 I Suppl 1 I Suppl 1 S5-9 22 1978 751 23 1998 24 2009 25 2017 26 1962 27 2011 28 2011 29 World Health Organisation 2005 30 2018 122 3 3 210-6 31 OCDE 2018 32 2016 21 6 6 651-3 33 American Society of Clinical Oncology 2015 33 23 23 2563-77 34 2008 27 4 4 826-42 35 1954 36 1991 37 1995 38 1930 39 2013 2 2 2 189-98 40 1997 2 41 1986 5 1 1 1-30 42 2003 27 1 1 5-76 43 1963 53 5 5 941-73 44 2013 3 45 2009 6 46 2003 12 1 1 3-16 47 2003 12 8 8 609-28 48 2008 17 5 5 607-17 49 1991 17 1 1 1-23 50 1972 80 2 2 223-55 51 1972 52 2018 21 2 2 124-30 53 2013 2 2 2 189-98 54 2002 2 4 4 319-26 55 2018 7 2 2 120-36 56 2018 21 2 2 131-9 57 2018 21 2 2 146-54 58 2015 1-3 59 2014 59 6 6 399-412