<?xml version="1.0" encoding="ISO-8859-1"?><article xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance">
<front>
<journal-meta>
<journal-id>2795-5001</journal-id>
<journal-title><![CDATA[Portuguese Journal of Dermatology and Venereology]]></journal-title>
<abbrev-journal-title><![CDATA[Port J Dermatol Venereol.]]></abbrev-journal-title>
<issn>2795-5001</issn>
<publisher>
<publisher-name><![CDATA[Permanyer Publications]]></publisher-name>
</publisher>
</journal-meta>
<article-meta>
<article-id>S2795-50012025000100022</article-id>
<article-id pub-id-type="doi">10.24875/pjdv.240000801</article-id>
<title-group>
<article-title xml:lang="en"><![CDATA[Histological profile of alopecia areata at a teaching hospital in Eastern India]]></article-title>
<article-title xml:lang="pt"><![CDATA[Perfil histológico da alopecia areata num hospital universitário no leste da Índia]]></article-title>
</title-group>
<contrib-group>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Bubna]]></surname>
<given-names><![CDATA[Aditya K.]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Viplav]]></surname>
<given-names><![CDATA[Vinayak]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
</contrib-group>
<aff id="Af1">
<institution><![CDATA[,Katihar Medical College Department of Dermatology ]]></institution>
<addr-line><![CDATA[ Bihar]]></addr-line>
<country>India</country>
</aff>
<pub-date pub-type="pub">
<day>00</day>
<month>03</month>
<year>2025</year>
</pub-date>
<pub-date pub-type="epub">
<day>00</day>
<month>03</month>
<year>2025</year>
</pub-date>
<volume>83</volume>
<numero>1</numero>
<fpage>22</fpage>
<lpage>27</lpage>
<copyright-statement/>
<copyright-year/>
<self-uri xlink:href="http://scielo.pt/scielo.php?script=sci_arttext&amp;pid=S2795-50012025000100022&amp;lng=en&amp;nrm=iso"></self-uri><self-uri xlink:href="http://scielo.pt/scielo.php?script=sci_abstract&amp;pid=S2795-50012025000100022&amp;lng=en&amp;nrm=iso"></self-uri><self-uri xlink:href="http://scielo.pt/scielo.php?script=sci_pdf&amp;pid=S2795-50012025000100022&amp;lng=en&amp;nrm=iso"></self-uri><abstract abstract-type="short" xml:lang="en"><p><![CDATA[Abstract  Objective: To describe the spectrum of histologic findings in AA among our study subjects.  Methods: This prospective, descriptive histological study was carried out over 1 year on 30 patients clinically diagnosed with AA. Two 4 mm punch biopsies were performed on each patient, with one being sectioned vertically and the other horizontally, following which each specimen was carefully analyzed.  Results: The classical &#8220;swarm of bees&#8221; outline was absent in all cases examined. The mean anagen to nonanagen ratio was 1:1.7. Nanogen follicles and miniaturized follicles were observed in 10 and 60% of the cases, respectively. Pigment incontinence was observed in 20% of the subjects, and follicular streamers and dilated follicular infundibula in 26.7 and 50% of the cases, respectively.  Conclusion: The absence of peribulbar lymphocytic infiltrates does not exclude the diagnosis of AA. Vertical sections may not be adequate for establishing a final diagnosis in all cases of AA. Transverse sections are required for the diagnosis of AA in long-standing cases, owing to greater number of follicular units available for microscopic examination.]]></p></abstract>
<abstract abstract-type="short" xml:lang="pt"><p><![CDATA[Resumo  Objetivo: Descrever o espectro de achados histológicos na AA.  Métodos: Estudo histopatológico prospetivo e descritivo, realizado ao longo de um período de 1 ano em 30 doentes com o diagnóstico clínico de AA. Foram efetuadas duas biópsias de 4 mm em cada caso, com uma amostra para cortes verticais e outra para cortes horizontais; após o que cada espécime foi cuidadosamente analisado em vários níveis.  Resultados: O padrão clássico de &#8220;enxame de abelhas&#8221; não foi detetado em nenhuma dos casos examinados. A proporção de folículos anagínicos: não anagénicos foi de 1:1,7. Folículos nanogénicos e folículos miniaturizados foram observados em 10% e 60% das biópsias, respectivamente. Incontinência pigmentar foi visualizada em 20% das biópsias avaliadas enquanto as estelas ou &#8220;rastos&#8221; foliculares (&#8220;streamers&#8221;) e infundíbulos foliculares ocorreram em 26.7% e 50% das seções, respetivamente.  Conclusão: A ausência de infiltrados linfocíticos peribulbares não permite excluir o diagnóstico de AA. As secções verticais podem não ser adequadas para estabelecer um diagnóstico final em todos os casos de AA. Os cortes transversais tornam-se obrigatórios para estabelecer um diagnóstico definitivo de AA em casos de longa evolução, devido ao maior número de unidades foliculares disponíveis para exame histopatológico.]]></p></abstract>
<kwd-group>
<kwd lng="en"><![CDATA[Alopecia areata]]></kwd>
<kwd lng="en"><![CDATA[Histology]]></kwd>
<kwd lng="en"><![CDATA[Transverse sections]]></kwd>
<kwd lng="en"><![CDATA[Vertical sections]]></kwd>
<kwd lng="pt"><![CDATA[Alopecia areata]]></kwd>
<kwd lng="pt"><![CDATA[Histologia]]></kwd>
<kwd lng="pt"><![CDATA[Cortes transversais]]></kwd>
<kwd lng="pt"><![CDATA[Seções verticais]]></kwd>
</kwd-group>
</article-meta>
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