<?xml version="1.0" encoding="ISO-8859-1"?><article xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance">
<front>
<journal-meta>
<journal-id>2795-5001</journal-id>
<journal-title><![CDATA[Portuguese Journal of Dermatology and Venereology]]></journal-title>
<abbrev-journal-title><![CDATA[Port J Dermatol Venereol.]]></abbrev-journal-title>
<issn>2795-5001</issn>
<publisher>
<publisher-name><![CDATA[Permanyer Publications]]></publisher-name>
</publisher>
</journal-meta>
<article-meta>
<article-id>S2795-50012026000100042</article-id>
<article-id pub-id-type="doi">10.24875/pjdv.25000058</article-id>
<title-group>
<article-title xml:lang="en"><![CDATA[Multiple arcuate lesions over neck of an adult: a case of atypical elastosis perforans serpiginosa]]></article-title>
<article-title xml:lang="pt"><![CDATA[Múltiplas lesões em arco no pescoço de um adulto: um caso atípico de elastose perfurante serpiginosa]]></article-title>
</title-group>
<contrib-group>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Pal]]></surname>
<given-names><![CDATA[Shrayan]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Maiti]]></surname>
<given-names><![CDATA[Swarnali]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
</contrib-group>
<aff id="Af1">
<institution><![CDATA[,ICARE Institute of Science and Research Venereology and Leprosy Department of Dermatology]]></institution>
<addr-line><![CDATA[Kolkata ]]></addr-line>
<country>India</country>
</aff>
<aff id="Af2">
<institution><![CDATA[,Barasat Government Medical College Venereology and Leprosy Department of Dermatology]]></institution>
<addr-line><![CDATA[Kolkata ]]></addr-line>
<country>India</country>
</aff>
<pub-date pub-type="pub">
<day>00</day>
<month>03</month>
<year>2026</year>
</pub-date>
<pub-date pub-type="epub">
<day>00</day>
<month>03</month>
<year>2026</year>
</pub-date>
<volume>84</volume>
<numero>1</numero>
<fpage>42</fpage>
<lpage>45</lpage>
<copyright-statement/>
<copyright-year/>
<self-uri xlink:href="http://scielo.pt/scielo.php?script=sci_arttext&amp;pid=S2795-50012026000100042&amp;lng=en&amp;nrm=iso"></self-uri><self-uri xlink:href="http://scielo.pt/scielo.php?script=sci_abstract&amp;pid=S2795-50012026000100042&amp;lng=en&amp;nrm=iso"></self-uri><self-uri xlink:href="http://scielo.pt/scielo.php?script=sci_pdf&amp;pid=S2795-50012026000100042&amp;lng=en&amp;nrm=iso"></self-uri><abstract abstract-type="short" xml:lang="en"><p><![CDATA[Abstract Elastosis perforans serpiginosa (EPS) is a rare disorder of the skin, usually present in early adulthood over the neck, upper arms, or face, associated with various genetic, cardiac, and renal comorbidities. A 38-year-old male presented with multiple painless, intensely itchy lesions over the neck for 6 months with insidious onset and gradually progressive number. There was no significant drug history or family history, or associated comorbidities or history of any intellectual disability. On examination, multiple non-tender arcuate plaques were present over the nape of the neck, without any scaling or ulceration. Due to a diagnostic dilemma, a biopsy was done, which showed elongated rete ridges forming a channel containing basophilic debris with numerous thick twisted wavy fibers with lymphocytic infiltrates. Verhoeff-Van Gieson staining came positive for elastic fibers. Hence, the case was diagnosed as idiopathic elastosis perforance serpiginosa. Lesions resolved after application of 0.05% tretinoin cream for 3 months. EPS is an uncommon disease of childhood or early adulthood, usually asymptomatic and associated with various genetic, cardiac, or renal comorbidities or drug intake. But here, lesions appeared at late adulthood, were intensely pruritic with no associated factors. Hence, the case was atypical in terms of onset, symptoms, and causal association; hence presented here.]]></p></abstract>
<abstract abstract-type="short" xml:lang="pt"><p><![CDATA[Resumo A elastose perfurante serpiginosa é uma doença rara da pele que geralmente se manifesta no início da idade adulta, afetando o pescoço, os braços superiores ou o rosto, e está associada a várias comorbidades genéticas, cardíacas e renais. Um homem de 38 anos apresentou múltiplas lesões indolores e intensamente pruriginosas no pescoço há seis meses, de início insidioso e número progressivamente crescente. Não havia histórico significativo de uso de medicamentos, antecedentes familiares, comorbidades associadas ou deficiência intelectual. Ao exame físico, observaram-se múltiplas placas arqueadas não dolorosas na nuca, sem descamação ou ulceração. Devido ao dilema diagnóstico, foi realizada biópsia que revelou cristas epidérmicas alongadas formando um canal contendo detritos basofílicos, com numerosas fibras espessas, torcidas e onduladas, além de infiltrado linfocitário. A coloração de Verhoeff-Van Gieson foi positiva para fibras elásticas. Assim, o caso foi diagnosticado como elastose perfurante serpiginosa idiopática. As lesões regrediram após aplicação de creme de tretinoína a 0,05% por três meses. A elastose perfurante serpiginosa é uma doença incomum da infância ou início da idade adulta, geralmente assintomática e associada a diversas comorbidades genéticas, cardíacas, renais ou ao uso de medicamentos. No entanto, neste caso, as lesões surgiram tardiamente na idade adulta, eram intensamente pruriginosas e sem fatores associados, configurando, portanto, uma apresentação atípica quanto ao início, sintomas e causa.]]></p></abstract>
<kwd-group>
<kwd lng="en"><![CDATA[Elastosis perforans serpiginosa]]></kwd>
<kwd lng="en"><![CDATA[Arcuate]]></kwd>
<kwd lng="en"><![CDATA[Elastin]]></kwd>
<kwd lng="en"><![CDATA[Verhoeff-Van Gieson]]></kwd>
<kwd lng="en"><![CDATA[Basophilic debris]]></kwd>
<kwd lng="pt"><![CDATA[Elastose perfurante serpiginosa]]></kwd>
<kwd lng="pt"><![CDATA[Arqueado]]></kwd>
<kwd lng="pt"><![CDATA[Elastina]]></kwd>
<kwd lng="pt"><![CDATA[Verhoeff-Van Gieson]]></kwd>
<kwd lng="pt"><![CDATA[Detritos basofílicos]]></kwd>
</kwd-group>
</article-meta>
</front><back>
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