<?xml version="1.0" encoding="ISO-8859-1"?><article xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance">
<front>
<journal-meta>
<journal-id>2795-5001</journal-id>
<journal-title><![CDATA[Portuguese Journal of Dermatology and Venereology]]></journal-title>
<abbrev-journal-title><![CDATA[Port J Dermatol Venereol.]]></abbrev-journal-title>
<issn>2795-5001</issn>
<publisher>
<publisher-name><![CDATA[Permanyer Publications]]></publisher-name>
</publisher>
</journal-meta>
<article-meta>
<article-id>S2795-50012026000100056</article-id>
<article-id pub-id-type="doi">10.24875/pjdv.25000081</article-id>
<title-group>
<article-title xml:lang="en"><![CDATA[Spitz nevus: a case report of a benign melanocytic neoplasm with a review of recent advances]]></article-title>
<article-title xml:lang="pt"><![CDATA[Nevo de Spitz: relato de caso de uma neoplasia melanocítica benigna com revisão dos avanços recentes]]></article-title>
</title-group>
<contrib-group>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Kumar-Gupta]]></surname>
<given-names><![CDATA[Sunil]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
</contrib-group>
<aff id="Af1">
<institution><![CDATA[,All India Institute of Medical Sciences Department of Dermatology and Venereology ]]></institution>
<addr-line><![CDATA[Gorakhpur ]]></addr-line>
<country>India</country>
</aff>
<pub-date pub-type="pub">
<day>00</day>
<month>03</month>
<year>2026</year>
</pub-date>
<pub-date pub-type="epub">
<day>00</day>
<month>03</month>
<year>2026</year>
</pub-date>
<volume>84</volume>
<numero>1</numero>
<fpage>56</fpage>
<lpage>58</lpage>
<copyright-statement/>
<copyright-year/>
<self-uri xlink:href="http://scielo.pt/scielo.php?script=sci_arttext&amp;pid=S2795-50012026000100056&amp;lng=en&amp;nrm=iso"></self-uri><self-uri xlink:href="http://scielo.pt/scielo.php?script=sci_abstract&amp;pid=S2795-50012026000100056&amp;lng=en&amp;nrm=iso"></self-uri><self-uri xlink:href="http://scielo.pt/scielo.php?script=sci_pdf&amp;pid=S2795-50012026000100056&amp;lng=en&amp;nrm=iso"></self-uri><abstract abstract-type="short" xml:lang="en"><p><![CDATA[Abstract Spitz nevus is a rare benign melanocytic lesion that can clinically mimic benign and malignant dermatological conditions. We report a case of a 22-year-old female who presented with a long-standing, asymptomatic nodule on her left cheek. The lesion was excised due to cosmetic concerns, and histopathological analysis confirmed the diagnosis of Spitz nevus. Given its clinical resemblance to malignant conditions, a complete surgical excision was performed for definitive diagnosis and cosmetic management. Recent studies highlight advances in molecular diagnostics and immunohistochemistry, which help differentiate Spitz nevus from malignant melanocytic neoplasms. This case underscores the necessity of histopathological and molecular evaluation in distinguishing Spitz nevus from other pigmented lesions.]]></p></abstract>
<abstract abstract-type="short" xml:lang="pt"><p><![CDATA[Resumo O nevo de Spitz é uma lesão melanocítica benigna rara que pode mimetizar clinicamente condições dermatológicas benignas e malignas. Relata-se o caso de uma doente de 22 anos que apresentava um nódulo assintomático de longa data na face esquerda. A lesão foi excisada devido a preocupações estéticas, e a análise histopatológica confirmou o diagnóstico de nevo de Spitz. Dada a semelhança clínica com condições malignas, foi realizada uma excisão cirúrgica completa para diagnóstico definitivo e tratamento estético. Estudos recentes destacam os avanços no diagnóstico molecular e na imunohistoquímica, que auxiliam na diferenciação do nevo de Spitz das neoplasias melanocíticas malignas. Este caso realça a necessidade de avaliação histopatológica e molecular para distinguir o nevo de Spitz de outras lesões pigmentadas.]]></p></abstract>
<kwd-group>
<kwd lng="en"><![CDATA[Nevus]]></kwd>
<kwd lng="en"><![CDATA[Benign melanocytic tumor]]></kwd>
<kwd lng="en"><![CDATA[Spitz tumor]]></kwd>
<kwd lng="pt"><![CDATA[Nevo]]></kwd>
<kwd lng="pt"><![CDATA[Tumor melanocítico benigno]]></kwd>
<kwd lng="pt"><![CDATA[Tumor de Spitz]]></kwd>
</kwd-group>
</article-meta>
</front><back>
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</article>
