Introduction:

The relationship between asthma and obesity is complex and multifactorial. Obesity is a risk factor for asthma and is associated with more severe disease, poor response to treatment, and more frequent exacerbations. Bariatric surgery is the most effective way to lose weight. Several studies report improvement in asthma control and lung function, reduction in medication and number of exacerbations, and improvement in quality of life.

Objectives:

To investigate the efficacy of bariatric surgery in controlling asthma in obese patients.

Methods:

Adult patients with uncontrolled asthma and Body Mass Index (BMI) >30 kg/m2 who were unable to lose weight through lifestyle changes and medical treatment will be selected to undergo bariatric surgery. Clinical data will be collected to ascertain eligibility, and written consent will be obtained. Included subjects will be assessed in terms of asthma control, medication use, lung function and quality of life, before bariatric surgery and after 1 year, during follow-up appointment.

Analysis:

Results will be presented with scores according to the Asthma Control Test (ACT), Control of Allergic Rhinitis and Asthma Test (CARAT), and Mini Asthma Quality of Life Questionnaire (MiniAQLQ), as well as a number of exacerbations, systemic corticosteroids (SCS), medication step-up/down and lung function. Statistical analysis will be conducted, and a p-value <0.05 will be considered statistically significant Ethics: The study will be carried out in accordance with Good Clinical Practice as required by the Declaration of Helsinki.

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