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Acta Obstétrica e Ginecológica Portuguesa

versão impressa ISSN 1646-5830


PEIXINHO, Catarina et al. Follicle-stimulating-hormone-secreting pituitary macroadenoma: a challenging diagnosis in gynecology. Acta Obstet Ginecol Port [online]. 2020, vol.14, n.4, pp.257-262.  Epub 01-Dez-2020. ISSN 1646-5830.

Menstrual irregularities account for up to 30% of outpatient visits to gynecologists. We present a case of a 29-year-old nulliparous woman with abnormal vaginal bleeding for the last five years. A transvaginal ultrasound revealed both ovaries enlarged with multiple cysts. Blood tests showed mildly elevated levels of estradiol and prolactin, and a suppressed LH. Cerebral MRI showed a pituitary macroadenoma. The patient was submitted to transsphenoidal surgery. The final diagnosis was pituitary adenoma with FSH and LH expression. Cases of pituitary adenomas causing clinical symptoms are unusual This diagnosis should be considered in women with menstrual irregularities and hyperstimulated ovaries.

Palavras-chave : Follicle-stimulating-hormone; Pituitary macroadenoma; Menstrual irregularities; Ovarian hyperstimulation; Reproductive age..

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