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Acta Obstétrica e Ginecológica Portuguesa

versión impresa ISSN 1646-5830


RAMOS, Rui; CAMPELOS, Sofia  y  FONSECA-MOUTINHO, José. Toker Cell Hyperplasia: a case report. Acta Obstet Ginecol Port [online]. 2021, vol.15, n.2, pp.183-188.  Epub 30-Jun-2021. ISSN 1646-5830.

Toker cells are epithelial cells of the nipple epidermis, with a prevalence of about 10% of nipple sections stained with hematoxylin and eosin (H&E). More rarely, these cells are found in increased number, phenomenon known by Toker cell hyperplasia (TCH). TCH is a benign condition not associated with clinical manifestations. Reports regarding TCH refer to it as an incidental finding in skin biopsies, associated with other diseases, particularly, Paget’s Disease (PD). We report a case confirmed of TCH in a nipple associated with a non-specific chronic inflammatory lesion, with at least 17-year evolution. We emphasize the importance of biopsy to obtain a definitive diagnosis.

Palabras clave : Nipple; Clear cells; Hyperplasia; Incidental findings; Differential diagnosis.

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