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GE-Portuguese Journal of Gastroenterology

versión impresa ISSN 2341-4545

Resumen

BOTTO, Inês et al. Hepatocellular Carcinoma with Vascular and Cardiac Involvement in a Young Patient with Non-Cirrhotic Hepatitis B: A Case Report. GE Port J Gastroenterol [online]. 2025, vol.32, n.2, pp.42-46.  Epub 15-Mayo-2025. ISSN 2341-4545.  https://doi.org/10.1159/000539093.

Introduction:

Hepatocellular carcinoma (HCC) is a highly vascular malignancy with the potential for intravascular invasion. However, vascular extension into the cardiac chambers is extremely rare.

Case Presentation:

We present a 25-year-old male patient in whom the investigation of a cardiac murmur led to the discovery of an intracardiac mass that proved to be advanced-stage HCC with vascular invasion of the right heart. The patient had a previously unknown non-cirrhotic chronic hepatitis B virus (HBV) infection. Despite antiviral therapy and systemic treatment for HCC, he eventually died about 1 month later due to disease progression.

Conclusion:

This report highlights the importance of early HBV diagnosis and treatment for timely detection and management of HCC. Advanced-stage HCC, particularly with cardiac involvement, has an extremely poor prognosis.

Palabras clave : Hepatocellular carcinoma; Hepatitis B virus; Right atrial extension.

        · resumen en Portugués     · texto en Inglés     · Inglés ( pdf )