Abstract

OLIVEIRA, Raquel et al. Case of Flexural Exanthema as a Presenting Sign for COVID-19. Rev Soc Port Dermatol Venereol [online]. 2020, vol.78, n.3, pp.69-72.  Epub Sep 01, 2021. ISSN 2182-2395.  https://doi.org/10.29021/spdv.78.3.1248.

We report a case of a 84-year-old male hospitalized for bacterial pneumonia who, during hospitalization, developed a flexural exanthema in parallel with a positive swab for SARS-CoV-2. Supportive therapy was instituted, the rash disappeared in 7 days and the patient fully recovered. At the same time, two other cases of SARS-CoV-2 infection occurred in the same ward.

Histopathology and immunohistochemistry of a skin biopsy showed a scarce predominantly perivascular lymphocytic infiltration in the upper dermis, predominantly by CD4+ T cells, a slight epidermotropism, spongiosis and focal parakeratosis, compatible with a viral exanthema or a maculopapular drug eruption. Patch testing with possible culprit drugs were negative.

We seek to add value in understanding all the manifestations of SARS-CoV-2 infection and to draw attention to the importance of early identification of skin manifestations in association with COVID-19.

Keywords : Coronavirus Infections; COVID-19; Exanthema; SARS-CoV-2..

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